Results 191 to 200 of about 476,194 (255)

Gasdermin D antagonizes immunosuppression in prostate cancer by inducing LAMC2 degradation to block M2 macrophage polarization. [PDF]

J Immunother Cancer
Du Q, Han Z, Zhang Y, Li Y, Sun A, Wang B, Chen Y, Wang X.   +7 more
europepmc   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Requirement for written informed consent and selection bias in a chart-review prostate cancer study. [PDF]

Am J Epidemiol
Zheng R, Das SK, Tran TD, Friedrich NA, Cummings SM, Gonzalez A, De Hoedt AM, Bellerose H, Hoffmeyer A, Van de Ven TJ, Freedland SJ.   +10 more
europepmc   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Targeting the ELF1/EGFR/ERK positive feedback loop overcomes resistance to androgen receptor inhibition in AR-Vs positive prostate cancer. [PDF]

Neoplasia
Zhou M, Deng L, Chen X, Yang G, Huang Y, Zhang C, Yang Y, Mo Y, Li Z, Luo S, Zhang Q, Wang S.   +11 more
europepmc   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Cohort profile: BioCaPPE (Biomarkers of Prostate Cancer/Prevention and Environment) - a Canadian multicentre prospective study of lifestyle and candidate biomarkers in relation to prostate cancer risk. [PDF]

BMJ Open
Moussa H, Tourigny R, Robitaille K, Bussières V, Fadel J, Ben Souilah F, Diabaté L, Hovington H, Bettan L, Lacombe L, Dujardin T, Lodde M, Toren P, Aprikian A, Saad F, Carmel M, Jeldres C, Lamarche B, Bergeron A, Fradet Y, Fradet V, Network BIOCaPPE.   +21 more
europepmc   +1 more source

Periprostatic adipose tissue-derived adipokine profile in prostate cancer patients reveals two distinct molecular phenotypes linked to obesity-related comorbidities: multifaceted role of lipocalin-2. [PDF]

Cell Commun Signal
Pérez-Gómez JM, Prats-Escribano A, Gil-Duque I, Arroyo-Millán L, Huertas-Cabrera H, Núñez-Santos MA, López-Ruiz DJ, Mata-Ordoñez F, González-Serrano T, Ortea I, Porcel-Pastrana F, Álvarez-Benito M, Planque M, Carrasco-Valiente J, Gómez-Gómez E, Guzmán-Ruiz R, Fuentes-Fayos AC, Fendt SM, Gahete MD, Sarmento-Cabral A, Malagón MDM, Luque RM.   +21 more
europepmc   +1 more source

PCA Invite to 48th Annual PCA Conference, 11/11/2016

, 2016
Pennsylvania Counseling Association (PCA)
core  

Systematic Scale-Up of Mechanochemical Paracetamol-Oxalic Acid Cocrystal Synthesis across Multiple Milling Technologies. [PDF]

Org Process Res Dev
Schöbel JH, Gopinath D, Felderhoff M.
europepmc   +1 more source