Results 81 to 90 of about 919,275 (319)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Principal Component Analysis studies of turbulence in optically thick gas

, 2015
In this work we investigate the Principal Component Analysis (PCA) sensitivity to the velocity power spectrum in high opacity regimes of the interstellar medium (ISM). For our analysis we use synthetic Position-Position-Velocity (PPV) cubes of fractional
Burkhart, Blakesley, Correia, Caio, De Medeiros, José Renan, Lazarian, Alex, Pogosyan, Dmitri   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Yield and vegetation index of different maize varieties and nitrogen doses under normal irrigation

Open Agriculture
Nitrogen is essential nutrient that supports the growth and yield of corn. The correct dose of nitrogen fertilization is one of the keys to increasing corn productivity by its yield potential.
Padjung Rusnadi, Farid Muh., Musa Yunus, Nasaruddin Nasaruddin, Nurfaida Nurfaida, Anshori Muhammad Fuad, Achmad Mahmud, Arinong Abdul Rahman, Amier Nirwansyah   +8 more
doaj   +1 more source

Identification of Abnormal data in online dissolved gas monitoring in oil based on PCA and Fast-MCD

Zhejiang dianli
To detect the operational status of transformers by online monitoring of dissolved gases in oil is critical for ensuring its stable operation. However， faults in monitoring devices can result in abnormal data， severely impacting the effect of online ...
WANG Ziling, WANG Ke, CHAI Weijian, LI Yexin, ZOU Guoping, AN Siguang   +5 more
doaj   +1 more source

Size Distribution and Source Identification of Airborne Particulate Matter and Metallic Elements in a Typical Industrial City

Asian Journal of Atmospheric Environment, 2010
The size distribution of airborne particulate matter (PM) and the concentrations of associated metallic elements were investigated in a busy urban region of a typical Korean industrial city.
Mai Tra Ny , Byeong-Kyu Lee
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

GENETIC DIVERSITY IN SODIUM AZIDE INDUCED WHEAT MUTANTS STUDIED BY SSR MARKERS

Trakya University Journal of Natural Sciences, 2018
Mutations induced artificially way are one of the tools used to increase genetic variation in populations where genetic variation has been shrinking especially due to various reasons one of which is domestication.
Fatma Sarsu, Ayşe Şen
doaj   +1 more source

Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension. [PDF]

, 2017
Objective:Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p)YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in ...
Collak, Filiz Kisaayak, Demir, Ummuhan, Kurum, Esra, Ozkanli, Seyma, Zerk, Pinar Engin   +4 more
core  

PCA and K-Means decipher genome

, 2008
In this paper, we aim to give a tutorial for undergraduate students studying statistical methods and/or bioinformatics. The students will learn how data visualization can help in genomic sequence analysis.
A Zinovyev, AN Gorban, AN Gorban, AN Gorban, AY Zinovyev, FHC Crick, HY Ou, J Jackson, R Staden   +8 more
core   +2 more sources