Results 191 to 200 of about 350,311 (304)

Outcomes of Percutaneous Coronary Intervention in Patients with Inflammatory Bowel Disease. [PDF]

open access: yesJ Clin Med
Bhagat U   +8 more
europepmc   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito   +6 more
wiley   +1 more source

Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. [PDF]

open access: yesFront Immunol
Kozlíková M   +6 more
europepmc   +1 more source

Stepwise mitochondria‐targeted photodynamic immunotherapy enabled by an outer membrane vesicles‐based nanoplatform for synergistic tumor ablation and immune reprogramming

open access: yesSmart Molecules, EarlyView.
We constructed a novel excellent photodynamic drug without heavy atoms based on the conventional BODIPY photosensitizer, and then obtained a photodynamic vesicle with efficient tumor targeting (BDPM@OMVs) by bacterial extravasation. Multiple reactive oxygen species were efficiently generated under light irradiation, and the spontaneous elimination of ...
Xiang Cheng   +11 more
wiley   +1 more source

Mechanics‐based model for cold joints in reinforced concrete members

open access: yesStructural Concrete, EarlyView.
Abstract This study introduces a mechanics‐based numerical model to characterize the behavior of cold joints in reinforced concrete members subjected to monotonic loading. The model incorporates mechanisms such as interface slip and opening, aggregate interlock, clamping force, and dowel action of the reinforcing bars crossing the interface.
Brandon Li   +3 more
wiley   +1 more source

Nocturnal neighbors: exploring residents' perceptions of urban wildlife related to animal traits identified by camera traps and literature

open access: yesWildlife Biology, EarlyView.
Wildlife in urban areas is often a source of conflict, yet relatively few efforts have been directed toward fostering coexistence in these human‐dominated landscapes. While previous research has focused on socio‐demographic factors influencing perceptions of wildlife, the role of specific animal traits in shaping acceptance remains underexplored.
Simon S. Moesch   +3 more
wiley   +1 more source

Changes of Potential Suitable Areas for Lynx Under Climate Change in Mohe Area, Daxing'anling Mountains, China

open access: yesWildlife Letters, EarlyView.
Climate change drives shifts in suitable habitats for Eurasian lynx and its prey (hare, roe deer) in Mohe, Daxing'anling Mountains. Under RCP scenarios, moderate warming (RCP4.5) promotes substantial habitat expansion, while high‐emission conditions (RCP8.5) lead to strong expansion in the 2050s but slower gains and partial contraction by the 2070s ...
Binglian Liu   +5 more
wiley   +1 more source

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