Results 101 to 110 of about 91,335 (240)

Nanopore Electroporation: A New Delivery Method Within the Field of Epigenetic Editing

open access: yesSmall, EarlyView.
Nanopore‐mediated electroporation was used to deliver a CRISPRi system to clonal β‐cells. This enabled targeted downregulation of insulin expression while maintaining high cell viability. ABSTRACT Epigenetic modifications influence gene expression and contribute to type 2 diabetes (T2D), but establishing causality requires targeted modulation of ...
Frida Ekstrand   +7 more
wiley   +1 more source

Phenazine-1-Carboxamide Production in the Biocontrol Strain Pseudomonas chlororaphis PCL1391 Is Regulated by Multiple Factors Secreted into the Growth Medium

open access: yesMolecular Plant-Microbe Interactions, 2001
Pseudomonas chlororaphis PCL1391 controls tomato foot and root rot caused by Fusarium oxysporum f. sp. radicislycopersici. The production of phenazine-1-carboxamide (PCN) is crucial for this biocontrol activity.
Thomas F. C. Chin-A-Woeng   +7 more
doaj   +1 more source

External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications

open access: yesSmall, EarlyView.
Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko   +6 more
wiley   +1 more source

Extensive literature search on the PCN and PCN‐host interaction [PDF]

open access: yesEFSA Supporting Publications, 2012
Björn Niere, Jens‐Georg Unger
openaire   +1 more source

A Interdisciplinaridade Segundo Os Pcns

open access: yesRevista de Educação Pública, 2012
Este artigo tem como objetivo analisar os sentidos relacionados ao conceito de interdisciplinaridade nos Parâmetros Curriculares Nacionais (PCNs) de Ensino Fundamental e Ensino Médio. Utilizamos um método de análise conceitual, proposto por Coombs e Daniels, que possibilita investigar um conceito em um conjunto de textos.
openaire   +3 more sources

Engineering and systems-level analysis of Pseudomonas chlororaphis for production of phenazine-1-carboxamide using glycerol as the cost-effective carbon source

open access: yesBiotechnology for Biofuels, 2018
Background Glycerol, an inevitable byproduct of biodiesel, has become an attractive feedstock for the production of value-added chemicals due to its availability and low price.
Ruilian Yao   +5 more
doaj   +1 more source

Gastrointestinal obstruction secondary to chronic obstructive nephrolithiasis: A case report

open access: yesUroPrecision, EarlyView.
Abstract Background Nephrolithiasis is a common urologic condition, with increasing prevalence in the United States. This can often present with flank pain and hematuria; however, sequelae such as hydroureteronephrosis, forniceal rupture, and pyelonephritis can lead to more severe complications.
Jacob Galan   +2 more
wiley   +1 more source

Comorbidity Pattern in Patients with Moderate-to-Severe Plaque Psoriasis: Network Analysis of a Hospitalized Database in China

open access: yesClinical, Cosmetic and Investigational Dermatology
Wenjuan Chen,1– 3,* Jianfeng Zheng,2,3,* Xin Wang,2,3,* Xingzi Li,2,3 Yangfeng Ding,2,3 Chen Peng,1– 3 Yuling Shi2,3 1School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Department of Dermatology, Shanghai ...
Chen W   +6 more
doaj  

Holistic symptom burden and prognostic value of palliative care needs in heart failure: insights from the integrated palliative care outcome scale

open access: yesBMC Palliative Care
Introduction Heart failure (HF) patients experience significant palliative care needs (PCN), which can be assessed using the Integrated Palliative Care Outcome Scale (IPOS).
Do Thi Hien   +10 more
doaj   +1 more source

Interprofessional collaboration in diabetes care: perceptions of family physicians practicing in or not in a primary health care team

open access: yesBMC Family Practice, 2019
Background In Canada, most patients with type 2 diabetes mellitus (T2DM) are cared for in the primary care setting in the practices of family physicians.
Olga Szafran   +3 more
doaj   +1 more source

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