Results 101 to 110 of about 6,135 (256)

BNCC and PCNs for Portuguese Language: an analysis of the Curricular Component in High School

, 2023
Esta pesquisa busca compreender quais são os saberes valorizados pelos Parâmetros Curriculares Nacionais (PCNs) e pela Base Nacional Comum Curricular (BNCC) para o componente curricular de Língua Portuguesa do Ensino Médio, área de Linguagens e suas ...
Nascimento, Marina Guimarães [UNESP]
core  

Why HR Has Failed to Address Healthcare's Workforce Crisis: The Need for a Systems Partner Role

Human Resource Management Journal, EarlyView.
ABSTRACT Attempts to remedy sustained workforce challenges facing healthcare organizations globally have been largely ineffective, despite increased political attention. In this paper we draw on contextually based human resource theory to explain why these challenges remain intractable.
Aoife M. McDermott, Graeme Currie, Hector P. Rodriguez   +2 more
wiley   +1 more source

BTKi orelabrutinib improved the outcome of newly-diagnosed PCNS-LBCL by alleviating MyD88 L265P -induced PIM1 stability

Journal of Hematology & Oncology
Primary central nervous system large B-cell lymphoma (PCNS-LBCL) exhibits the worst prognosis among all extranodal LBCLs, with the enriched genetic mutations in MyD88 L265P , CD79B and PIM1.
Yan Yuan, Bo Dai, Haoshu Zhong, Jiajun Zheng, Zhen Fan, Di Chen, Qian Wang, Hao Wu, Yuan Li, Ping Zhu, Tianling Ding, Shu Wang, Kunpeng Wu, Yu Zhang, Zhenhua Wang, Rui Feng, Fengping Zhu, Kang Zheng, Zhiyong Qin, Bojie Yang, Hong Chen, Xiaolei Lin, Yu Yao, Dongxiao Zhuang, Zhifeng Shi, Ying Mao, Tong Chen   +26 more
doaj   +1 more source

Improving access to help with poor sleep across youth mental health services: Interim implementation and clinical outcomes

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives There is a high, unmet sleep need in young people with mental health difficulties. We took a whole‐system approach to improving access to sleep support across a youth mental health system (14–25 years). Methods We used the Exploration, Preparation, Implementation and Sustainment (EPIS) framework to develop an implementation ...
Rebecca Rollinson, Ben Ewing, Sarah Reeve, Adam Graham, Jonathan Lyons, Brioney Gee, Jonathon Wilson, Ioana Tofan, Kelly Semper, Tim Clarke   +9 more
wiley   +1 more source

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

Cell Proliferation, EarlyView.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang, Miao Xu, Yongshun Wang, Xuan Lin, Qiang Zhang, Xiaoning Lin, Xin Wu, Cheng Zhang, Wenhua Huang, Jianlin Shen   +9 more
wiley   +1 more source

Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies

Journal of Neuroinflammation
Background Immune dysregulation is a hallmark of autoimmune diseases of the central nervous system (CNS), characterized by an excessive immune response, and primary CNS tumors (pCNS-tumors) showing a highly immunosuppressive parenchymal microenvironment.
Saskia Räuber, Andreas Schulte-Mecklenbeck, Alice Willison, Ramona Hagler, Marius Jonas, Duygu Pul, Lars Masanneck, Christina B. Schroeter, Kristin S. Golombeck, Stefanie Lichtenberg, Christine Strippel, Marco Gallus, Andre Dik, Ruth Kerkhoff, Sumanta Barman, Katharina J. Weber, Stjepana Kovac, Melanie Korsen, Marc Pawlitzki, Norbert Goebels, Tobias Ruck, Catharina C. Gross, Werner Paulus, Guido Reifenberger, Michael Hanke, Oliver Grauer, Marion Rapp, Michael Sabel, Heinz Wiendl, Sven G. Meuth, Nico Melzer   +30 more
doaj   +1 more source

Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort

Endoscopy International Open, 2017
Background and study aims The American Gastroenterological Association (AGA) recently published guidelines for the management of asymptomatic pancreatic cystic neoplasms (PCNs). We aimed to evaluate the diagnostic characteristics of the AGA guidelines in
Phillip S. Ge, V. Raman Muthusamy, Srinivas Gaddam, Diana-Marie Jaiyeola, Stephen Kim, Alireza Sedarat, Timothy R. Donahue, Lindsay Hosford, Robert H. Wilson, David P. Grande, Rajesh N. Keswani, Vladimir M. Kushnir, Daniel Mullady, Steven A. Edmundowicz, Dayna S. Early, Srinadh Komanduri, Sachin Wani, Rabindra R. Watson   +17 more
doaj   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source

Occurrence, distribution and source apportionment of polychlorinated naphthalenes (PCNs) in sediments and soils from the Liaohe River Basin, China

, 2016
The occurrence and spatial distribution of polychlorinated naphthalenes (PCNs) were investigated in sediments, upland and paddy soils from the Liaohe River Basin.
Gao, Yuan, Li, Fang, Tan, Dongqin, Chen, Jiping, Jin, Jing, Zhang, Haijun, Geng, Ningbo, Ni, Yuwen   +7 more
core   +1 more source

Which Aspects of Abortion Care Do Healthcare Practitioners in Britain Think Nurses/Midwives Should Provide? Findings From the SACHA Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the views of healthcare practitioners in Britain regarding the role of midwives and nurses in the delivery of medical and surgical abortion. Design An observational study of the Shaping Abortion for Change study healthcare practitioner survey (2021–2022).
Alice Fulton, Ona McCarthy, Jill Shawe, Rebecca Meiksin, Maria Lewandowska, Melissa Palmer, Rachel Scott, Kaye Wellings, Patricia Lohr, Geoffrey Wong, Sally Sheldon, Rebecca French and The SACHA Study Team, Annette Aronsson, Paula Baraitser, Sharon Cameron, Louise Keogh, Clare Murphy, Wendy V. Norman, Jennifer Reiter, Natasha Salaria   +19 more
wiley   +1 more source