Results 41 to 50 of about 11,641 (223)
Evaluation of p53 Gene Mutations in Oral Lichen Planus Lesions in a Population From Iran
Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.ABSTRACT Objectives Oral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa, genetic and molecular alterations, including mutations in the p53 tumor suppressor gene, have been implicated in OLP pathogenesis. However, its molecular mechanisms are not clearly understood.
Erfan Jokar +6 more
wiley +1 more source
Mutation screening of exons 7 and 13 of the TMC1 gene in autosomal recessive non-syndromic hearing loss (ARNSHL) in Iran [PDF]
, 2016 Mutation screening of exons 7 and 13 of ...
Abolhasani, Marziyeh. +6 more
core +2 more sources
Ecology and Evolution, Volume 15, Issue 5, May 2025.We present results from a mesocosm experiment testing the utility of marine sponges as natural samplers of eDNA and show the effect of DNA state on the capture and persistence of genetic material. We find a significant interaction between DNA state and sample type, with lower detection and concentration of extracellular DNA, compared to cellular DNA ...
Rosalie Dowell +4 more
wiley +1 more source
BioTechniques, 2002 PCR single-stranded conformational polymorphism (SSCP) analysis is a simple and rapid electrophoretic technique for the sensitive detection of sequence variants of PCR products.
Koichiro Higasa +3 more
doaj +1 more source
Cancer Medicine, Volume 14, Issue 8, April 2025.ABSTRACT Background Genetic testing and sequencing technologies offer a comprehensive understanding of cancer genetics, providing rapid and cost‐effective solutions. In particular, these advanced technologies play an important role in assessing the complexities of the rare cancer types affecting several systems including the bone, endocrine, digestive,
Joviana Farhat +4 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2003 Point mutations and small insertions or deletions in the human alpha-globin genes may produce alpha-chain structural variants and alpha-thalassemia.
S.B. Jorge +3 more
doaj +1 more source
Origins of T‐cell‐mediated autoimmunity in acquired aplastic anaemia
British Journal of Haematology, Volume 206, Issue 4, Page 1035-1053, April 2025.Acquired aplastic anaemia (AA) is an autoimmune bone marrow failure disease caused by a cytotoxic T‐cell–mediated attack on haematopoietic stem and progenitor cells (HSPCs). Despite significant progress in understanding T‐cell repertoire alterations in AA, the identification of specific pathogenic T cells remains elusive.
Aura Enache +2 more
wiley +1 more source
Use of streptavidin magnetic beads in single strand conformation polymorphism profiles to detect mutations in rpoB gene of M.tuberculosis [PDF]
, 1998 Single strand conformation polymorphism (SSCP) is one of the promising techniques to identify mutations in short pieces of DNA (Orita et al. 1989). In this technique, DNA of interest is often amplified by the polymerase chain reaction (PCR) and then ...
Ding, B C +4 more
core
[PGM1 genotyping by PCR-SSCP].
Fa yi xue za zhi, 2004 PGM1 genotyping by PCR-SSCP analysis.Amplified genome DNA from 156 unrelated Han individuals living in Wuhan, PCR products for exon 4 and exon 8 of PGM1 were then analyzed by SSCP to detect the genotypes.2 alleles and 3 genotypes were detected in exon 4 and 8 respectively. The discrimination power was 0.7318.
Hai-yan, Song +2 more
openaire +1 more source
Cancer Reports, Volume 8, Issue 1, January 2025.ABSTRACT Background Changes in functional genetic polymorphisms may increase or decrease the risk of cancer in patients. Nowadays, the association between polymorphisms in the interleukin‐8 (IL‐8) gene and the susceptibility of cancer risk have been investigated in many studies, however, above relationships remain unclear. Aim The current study aims to
Bin Xu, Yidan Yan
wiley +1 more source