Results 31 to 40 of about 3,757,578 (294)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Investigating the mechanism of action of hemofugal and blood-stasis-expelling soup in the treatment of coronary heart disease based on network pharmacology [PDF]
BIO Web of ConferencesObjective: To investigate the mechanism of action of Xuefu yuyuxu Tang in the treatment of Coronary Heart Disease (CHD) based on network-based pharmacology.
·yusuf Arslan, Ma Yun, Wang Qi
doaj +1 more source
EPAM/CHREST tutorial: Fifty years of simulating human learning [PDF]
, 2009 Generating quantitative predictions for complex cognitive phenomena requires precise implementations of the underlying cognitive theory. This tutorial focuses on the EPAM/CHREST tradition, which has been providing significant models of human ...
Gobet, F, Lane, PCR
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Nanomaterials, 2022 Recently, metal oxide nanoparticles (NPs) have attracted attention as promising components for the protection and stimulation of plant microclones in tissue culture in vitro.
Tatiana A. Grodetskaya +7 more
doaj +1 more source
Computational models of the development of perceptual expertise [PDF]
, 2007 In a recent article, Palmeri, Wong and Gauthier have argued that computational models may help direct hypotheses about the development of perceptual expertise.
Campitelli, G, Gobet, F, Lane, PCR
core
Digital PCR as a tool to measure HIV persistence [PDF]
, 2018 Although antiretroviral therapy is able to suppress HIV replication in infected patients, the virus persists and rebounds when treatment is stopped.
Bosman, Kobus +4 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Applied SciencesSalmonella enterica subsp. enterica serovar Typhimurium is an important foodborne pathogen, and poultry products are a major source of human infection.
Antonio Martínez-Murcia +6 more
doaj +1 more source
International Journal of Nanomedicine, 2023 Nagwa SM Aly,1,2 Hye-Sook Kim,2 Yasmin M Marei,3 Azza S Elhamshary,1 Ibrahim R Bayoumi,4 Rabab E Omar,1 Dina A Mohammed,1 Shin-Ichi Miyoshi,5 Gehan A Rashed1 1Department of Parasitology, Benha Faculty of Medicine, Benha University, Benha, 13511, Egypt ...
Aly NS +8 more
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