Results 241 to 250 of about 40,773 (330)

Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels

, 2012
Michael T. Lipari, Wei Li, Paul Moran, Monica Kong-Beltran, Tao Sai, Joyce Lai, Seh‐Ching Lin, Ganesh Kolumam, Jose Zavala‐Solorio, Anita Izrael-Tomasevic, David Arnott, Jianyong Wang, Andrew S. Peterson, Daniel Kirchhofer   +13 more
openalex   +1 more source

Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan. [PDF]

Eur J Med Res
Tu KC, Chang WT, Lin HW, Lin PL, Wu YW, Lin CF, Yeh HI, Charng MJ, Huang PH, Lin TH, Lin WW, Hsieh IC, Kuo FY, Chen CP, Lin SH, Li YH.   +15 more
europepmc   +1 more source

Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats [PDF]

, 2014
Yanjun Jia, Rui-Xa Xu, Jing Sun, Yue Tang, Jian‐Jun Li   +4 more
openalex   +1 more source

Immunotherapy and vaccine-based approaches for atherosclerosis prevention: a systematic review study. [PDF]

BMC Cardiovasc Disord
Shekarchizadeh Esfahani M, Siavash M, Sajad RS, Ramezani Ahmadi A, Karimifar M, Akbari M, Shekarchizadeh M.   +6 more
europepmc   +1 more source

Definire il ruolo di PCSK9 nella fisiopatologia della malattia di Alzheimer: studio in vivo nel modello murino 5XFAD [PDF]

La malattia di Alzheimer (AD) è una patologia neurodegenerativa multifattoriale e rappresenta la causa più comune di demenza a livello globale. La maggior parte dei farmaci disponibili allevia solo transitoriamente i sintomi, e nuove terapie hanno ...
BODRIA, MARTINA
core  

The M2 Module of the Cys-His-rich Domain (CHRD) of PCSK9 Protein Is Needed for the Extracellular Low-density Lipoprotein Receptor (LDLR) Degradation Pathway

, 2012
Yascara Grisel Luna Saavedra, Robert Day, Nabil G. Seidah   +2 more
openalex   +1 more source

Causal relationship between drug target genes of LDL-cholesterol and coronary artery disease: drug target Mendelian randomization study. [PDF]

Lipids Health Dis
Jee Y, Shin JW, Ryu M, Song TJ.
europepmc   +1 more source

Association of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) With Cardiovascular Risk in Primary Prevention [PDF]

, 2015
Yiming M. Zhu, Todd J. Anderson, Khokan C. Sikdar, Marinda Fung, Matthew McQueen, Eva Lonn, Subodh Verma   +6 more
openalex   +1 more source

Beyond LDL-C lowering: Distinct molecular sphingolipids are good indicators of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency

, 2013
Minna T. Jänis, Kirill V. Tarasov, Hung Xuan Ta, Matti Suoniemi, Kim Ekroos, Reini Hurme, Terho Lehtimäki, Hannu Päivä, Marcus E. Kleber, Winfried März, Annik Prat, Nabil G. Seidah, Reijo Laaksonen   +12 more
openalex   +1 more source

The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis [PDF]

, 2015
Amélie Bonnefond, Loïc Yengo, Cédric Le May, Frédéric Fumeron, Michel Marre, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Philippe Froguel, Bertrand Cariou   +9 more
openalex   +1 more source