Results 91 to 100 of about 14,320 (287)

Epitope Mapping of the Major Capsid Protein of Type 2 Porcine Circovirus (PCV2) by Using Chimeric PCV1 and PCV2 [PDF]

Journal of Virology, 2004
ABSTRACT Type 2 porcine circovirus (PCV2) is associated with postweaning multisystemic wasting syndrome in pigs, whereas the genetically related type 1 PCV (PCV1) is nonpathogenic. In this study, seven monoclonal antibodies (MAbs) against PCV2-ORF2 capsid protein were generated, biologically characterized, and subsequently used to map the ...
Porntippa, Lekcharoensuk, Igor, Morozov, Prem S, Paul, Nattarat, Thangthumniyom, Worawidh, Wajjawalku, X J, Meng   +5 more
openaire   +2 more sources

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

Co-infecção por circovírus suíno tipo 2 e parvovírus suíno em fetos abortados e natimortos suínos no Sul do Brasil [PDF]

, 2007
Estudou-se retrospectivamente (2005-2007) a associação de casos de abortos e natimortos suínos com infecções por circovírus suíno (PCV) tipos 1 e 2 e parvovírus suíno (PPV). Outros agentes patogênicos foram pesquisados em amostras de fetos com lesões.
Antoniassi, Nadia Aline Bobbi, Bandarra, Paulo Mota, Castro, Luiza Amaral de, Cruz, Claúdio Estevão Farias da, Driemeier, David, Pescador, Caroline Argenta, Ravazzolo, Ana Paula, Sonne, Luciana   +7 more
core   +1 more source

First detection and phylogenetic analysis of porcine circovirus type 2 in raccoon dogs

BMC Veterinary Research, 2019
Background Porcine circovirus type 2 (PCV2) is a major emerging virus of porcine circovirus-associated disease (PCVAD), which has brought huge economic losses to the global pig industry. Pigs are well known as the natural reservoir of PCV2.
Tao Song, Jianxiang Hao, Ran Zhang, Menghu Tang, Wenao Li, Weirong Hui, Qiyuan Fu, Chunfang Wang, Shuyang Xin, Shoucong Zhang, Ping Rui, Hai Ren, Zengjun Ma   +12 more
doaj   +1 more source

Matrine exhibits antiviral activity in a PRRSV/PCV2 co-infected mouse model.

Phytomedicine, 2020
BACKGROUND PRRSV and PCV2 co-infection is very common in swine industry which results in huge economic losses worldwide. Although vaccination is used to prevent viral diseases, immunosuppression induced by PRRSV and PCV2 leads to vaccine failure ...
N. Sun, Hua Zhang, P. Sun, Ajab Khan, Jianhua Guo, Xiaozhong Zheng, Yaogui Sun, K. Fan, W. Yin, Hongquan Li   +9 more
semanticscholar   +1 more source

Fusion Expression and Immune Effect of PCV2 Cap Protein Tandem Multiantigen Epitopes with CD154/GM-CSF

Veterinary Sciences, 2021
Porcine circovirus associated diseases (PCVAD) is a contagious disease of swine caused by porcine circovirus type 2 (PCV2). The capsid protein (Cap) is the sole structural protein and the main antigen of PCV2. Cap is the principal immunogenic protein and
Qian Mao, Weijian Zhang, Shengming Ma, Zilong Qiu, Bingke Li, Chen Xu, Huang He, Shuangqi Fan, Keke Wu, Jinding Chen, Mingqiu Zhao   +10 more
semanticscholar   +1 more source

Development of a simple and high-yielding fed-batch process for the production of porcine circovirus type 2 virus-like particle subunit vaccine

AMB Express, 2019
The cap protein is encoded by the orf2 gene of porcine circovirus type 2 (PCV2) has the main antigen epitope of PCV2 and can form virus-like particles (VLPs), which are expressed in insect cells.
Wenlong Cao, Hui Cao, Xiaoping Yi, Yingping Zhuang   +3 more
doaj   +1 more source

Efficacy of Two Commercial Ready-To-Use PCV2 and Mycoplasma hyopneumoniae Vaccines under Field Conditions

Animals, 2021
Simple Summary Porcine Circovirus Type 2 (PCV2) and Mycoplasma hyopneumoniae are widespread pathogens which cause a negative health impact on swine and thus lead to important economic losses in farms.
G. López-Lorenzo, A. Prieto, Cynthia López-Novo, P. Díaz, C. López, P. Morrondo, G. Fernández, J. M. Díaz-Cao   +7 more
semanticscholar   +1 more source

Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2 [PDF]

BMC Veterinary Research, 2020
Abstract Background: Porcine circovirus type 2 (PCV2) is an immunosuppressive pathogen with high prevalence rate in pig farms. It has caused serious economic losses to the global pig industry. Due to the rapid mutation of PCV2 strain and co-infection of different genotypes, vaccination could not eradicate the infection of PCV2.
Yinlan Xu, Jiangang Zheng, Panpan Sun, Jianhua Guo, Xiaozhong Zheng, Yaogui Sun, Kuohai Fan, Wei Yin, Hongquan Li, Na Sun   +9 more
openaire   +5 more sources

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source