Results 181 to 190 of about 222,931 (262)

Reinforcement Learning for Jump‐Diffusions, With Financial Applications

Mathematical Finance, EarlyView.
ABSTRACT We study continuous‐time reinforcement learning (RL) for stochastic control in which system dynamics are governed by jump‐diffusion processes. We formulate an entropy‐regularized exploratory control problem with stochastic policies to capture the exploration–exploitation balance essential for RL.
Xuefeng Gao, Lingfei Li, Xun Yu Zhou
wiley   +1 more source

Anti-Inflammatory and Anti-apoptotic Effects of Phosphodiesterase Inhibitors Against Streptozocin-induced Diabetic Nephropathy. [PDF]

In Vivo
Mehanna OM, Elesawy BH, Elaskary A, Hassan MGM, Ahmed WMS, El Monsef ASA, Abbas MAM, Hammad AM, Elgazzar UB, Gabr NM, El-Sharnouby M, Sharahili AI, Khalifa MM.   +12 more
europepmc   +1 more source

The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition

New Phytologist, EarlyView.
Summary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Shunsuke Watanabe, Meijie Li, Alice Rossille, Chérhazad Boustani, Kevin Robe, Yuri Kanno, Mitsunori Seo, Christian Dubos   +7 more
wiley   +1 more source

Generative discovery of partial differential equations by learning from math handbooks. [PDF]

Nat Commun
Xu H, Chen Y, Cao R, Tang T, Du M, Li J, Callaghan AH, Zhang D.   +7 more
europepmc   +1 more source

Adverse Events in Nonsurgical Facial Aesthetic Procedures: A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical profile of treatment‐related adverse events (TRAE) associated with: (1) botulinum toxin in the upper face; (2) hyaluronic acid fillers in the lower face and nasolabial folds; and (3) nonsurgical facelifts with absorbable threads. Methods Searches were conducted in five electronic databases and
Vitória Maria Sousa Cruz, Sebastião Silvério Sousa‐Neto, Caique Mariano Pedroso, Maria Eduarda Pérez‐de‐Oliveira, Ana Gabriela Costa Normando, Helen Kaline Farias Bezerra, Rafael Tomaz Gomes, Ana Carolina Prado‐Ribeiro, Danyel Elias da Cruz Perez, Pablo Agustin Vargas, Alan Roger Santos‐Silva   +10 more
wiley   +1 more source

Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential. [PDF]

Bone Rep
Ursachi VC, Horak J, Fafilek B.
europepmc   +1 more source

Dotted Pigmentation of the Cuticle

Pediatric Dermatology, EarlyView.
ABSTRACT Longitudinal melanonychia in children is usually caused by nail matrix nevi and often fades over time. Pediatric patients with this finding are frequently referred to dermatologists due to concerns that it may represent melanoma. We report a case of a 4‐year‐old girl with longitudinal melanonychia on the left second fingernail, accompanied by ...
Anna Bolzon, Antonella Tosti
wiley   +1 more source

Divergent viral phosphodiesterases for immune signaling evasion. [PDF]

Cell Host Microbe
Doherty EE, Nomburg J, Adler BA, Lopez S, Hsieh K, Price N, Blount N, Doudna JA.   +7 more
europepmc   +1 more source

Enteral Green Beans in the Management of Neonatal Irritant Diaper Dermatitis

Pediatric Dermatology, EarlyView.
ABSTRACT Irritant diaper dermatitis (IDD) is frequently observed in neonatal intensive care units and is often exacerbated by chronic loose stools. Despite standard treatments, erosive or persistent IDD remains challenging to manage. We introduced pureed green beans into enteral feeds as a source of fiber to improve stool consistency and reduce skin ...
Allison Chiou, Lindsay Tufte, Matthew Mahoney, Christina Boull   +3 more
wiley   +1 more source

Modeling Metabolite Kinetics with a Partial Differential Equation-Based Hepatic Sinusoidal Model and MALDI-Mass Spectrometry Imaging of Verapamil and Its Metabolites. [PDF]

J Med Chem
Parise RJ, Chen B, Gibson CR, Cancilla MT, Nagar S, Korzekwa K.   +5 more
europepmc   +1 more source