Phosphodiesterases Regulate <i>C. elegans</i> Bitter Taste Avoidance. [PDF]
Sojka SE, Hammond FM, Ferkey DM.
europepmc +1 more source
ABSTRACT Aim To synthesize evidence on gingival diseases and conditions in children and adolescents (< 18 years) without known systemic disorder involvement, focusing on their distribution, aetiology, diagnosis, management and oral health–related quality of life (OHRQoL).
Georgios Tsilingaridis +4 more
wiley +1 more source
Exploring Patient Pathways and Care Situations in Men With Erectile Dysfunction in Different PDE-5 Inhibitor Regulatory Settings. [PDF]
May U, Werthner Q, Weigmann H, Bauer C.
europepmc +1 more source
Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns
Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng +5 more
wiley +1 more source
Learning image derived PDE-phenotypes from fMRI data. [PDF]
Bica I +5 more
europepmc +1 more source
ABSTRACT Veterinary graduates must be prepared to educate clients about medications and supplements. We surveyed 1955 Dog Aging Project newsletter recipients and 40 final‐year veterinary students at Texas A&M College of Veterinary Medicine and Biomedical Sciences on their perceptions about medications and supplements. Respondents indicated whether each
Sidonie T. Gallinger +31 more
wiley +1 more source
Peritoneal dialysis effluent biomarkers from a multi-omics and artificial intelligence perspective: advances and challenges. [PDF]
Li H +7 more
europepmc +1 more source
Measure‐valued processes for energy markets
Abstract We introduce a framework that allows to employ (non‐negative) measure‐valued processes for energy market modeling, in particular for electricity and gas futures. Interpreting the process' spatial structure as time to maturity, we show how the Heath–Jarrow–Morton approach can be translated to this framework, thus guaranteeing arbitrage free ...
Christa Cuchiero +3 more
wiley +1 more source
A novel therapy for pyridoxine-dependent epilepsy due to biallelic pathogenic variants in <i>ALDH7A1</i>: secondary mitochondrial energy deficiency and improvements of neurodevelopmental outcomes on triheptanoin treatment. [PDF]
Ambrose A +5 more
europepmc +1 more source
Reinforcement Learning for Jump‐Diffusions, With Financial Applications
ABSTRACT We study continuous‐time reinforcement learning (RL) for stochastic control in which system dynamics are governed by jump‐diffusion processes. We formulate an entropy‐regularized exploratory control problem with stochastic policies to capture the exploration–exploitation balance essential for RL.
Xuefeng Gao, Lingfei Li, Xun Yu Zhou
wiley +1 more source

