Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid +5 more
wiley +1 more source
Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential. [PDF]
Ursachi VC, Horak J, Fafilek B.
europepmc +1 more source
Building a Digital Twin for Material Testing: Model Reduction and Data Assimilation
ABSTRACT The rapid advancement of industrial technologies, data collection, and handling methods has paved the way for the widespread adoption of digital twins (DTs) in engineering, enabling seamless integration between physical systems and their virtual counterparts.
Rubén Aylwin +5 more
wiley +1 more source
cAMP/PKA signaling in endocrine hypertension: genetic mechanisms and pathophysiological insights. [PDF]
Lima Sobrinho JAB, Almeida MQ.
europepmc +1 more source
A Novel Mixed‐Hybrid, Higher‐Order Accurate Formulation for Kirchhoff–Love Shells
ABSTRACT This paper presents a novel mixed‐hybrid finite element formulation for Kirchhoff–Love shells, designed to enable the use of standard C0$C^0$‐continuous higher‐order Lagrange elements. This is possible by introducing the components of the moment tensor as a primary unknown alongside the displacement vector, circumventing the need for C1$C^1 ...
Jonas Neumeyer, Thomas‐Peter Fries
wiley +1 more source
Parameter identification for PDEs using sparse interior data and a recurrent neural network. [PDF]
Long J, Khaliq A, Furati KM.
europepmc +1 more source
A Compact Algorithm for Applying Periodic Boundary Conditions in 3D RVE Modeling with Abaqus
ABSTRACT Periodic boundary conditions (PBCs) are essential in multiscale modeling for computing the effective properties of heterogeneous materials via representative volume elements (RVEs). While several automated solutions have been developed for implementing PBCs in finite element software, many rely on structured node classification and predefined ...
Reza Sadeghpour, Martin Kraska
wiley +1 more source
Smoothness and stability in the Alt-Phillips problem. [PDF]
Carducci M, Tortone G.
europepmc +1 more source
Mode-Wise Spectral Criteria for Coupled Mass Transport in Hybrid PDE--ODE Tumor Microenvironments [PDF]
Jiguang Yu +3 more
openalex

