Results 71 to 80 of about 190,595 (336)

High-contrast imaging constraints on gas giant planet formation - The Herbig Ae/Be star opportunity

, 2015
Planet formation studies are often focused on solar-type stars, implicitly considering our Sun as reference point. This approach overlooks, however, that Herbig Ae/Be stars are in some sense much better targets to study planet formation processes ...
A. Boccaletti, A. Garufi, A. Garufi, A. Vigan, A.-M. Lagrange, A.-M. Lagrange, A.J. Skemer, A.L. Kraus, A.P. Verhoeff, A.S. Hales, A.W. Howard, B. Acke, B. Biller, B. Macintosh, B.A. Biller, B.P. Bowler, B.R. Oppenheimer, C. Marois, C. Marois, C. Marois, C. Pinte, C. Walsh, C.A. Grady, C.A. Grady, C.A. Grady, D.R. Ardila, D.S. Spiegel, E. Pantin, E.L. Nielsen, F. Fressin, F. Joos, F. Pepe, G. Chauvin, G. Witzel, G.D. Mulders, G.M. Kennedy, H. Avenhaus, H. Avenhaus, H. Canovas, H.M. Schmid, H.M. Schmid, I. Baraffe, J. Bouwman, J. Carson, J. Hashimoto, J. Rameau, J. Rameau, J. Rameau, J. Rameau, J. Tinbergen, J.-L. Beuzit, J.-L. Beuzit, J.A. Johnson, J.A. Johnson, J.A. Johnson, J.A. Johnson, J.C. Augereau, J.E. Pineda, J.M. Brown, J.R. Crepp, J.R. Kuhn, K.B. Follette, K.B. Follette, K.I. Öberg, K.M. Kratter, L.M. Close, L.M. Pérez, M. Fukagawa, M. Janson, M. Juan Ovelar de, M. Lambrechts, M. Min, M. Momose, M. Osorio, M. Reggiani, M.D. Perrin, M.S. Marley, N. Kusakabe, P. Pinilla, P. Pinilla, Q.M. Konopacky, R. Dong, S. Casassus, S. Hinkley, S. Ida, S. Reffert, S.D. Brittain, S.D. Brittain, S.M. Andrews, S.P. Quanz, S.P. Quanz, S.P. Quanz, S.P. Quanz, Sascha P. Quanz, T. Currie, T. Muto, T.J. Rodigas, W.J. Borucki, Z. Zhu, Z. Zhu   +99 more
core   +1 more source

Prolyl 4-hydroxlase activity is essential for development and cuticle formation in the human infective parasitic nematode Brugia malayi [PDF]

, 2013
Collagen prolyl 4-hydroxylases (C-P4H) are required for formation of extracellular matrices in higher eukaryotes. These enzymes convert proline residues within the repeat regions of collagen polypeptides to 4-hydroxyproline, a modification essential for ...
Alan D. Winter, Antony P. Page, Bendtsen, Cox, Ellgaard, Evans, Ghedin, Gillian McCormack, Hotez, Jex, Johanna Myllyharju, John, Kamath, Kelly, Kivirikko, Koivunen, Lamberg, Landmann, Lappi, Lok, Maule, Merriweather, Mitreva, Myllyharju, Myllyharju, Myllyharju, Opperman, Ottesen, Page, Petralanda, Pirneskoski, Rajan, Riihimaa, Stiernagle, Takacs, Timmons, Wang, Winter, Winter, Winter, Winter   +40 more
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Protein disulfide isomerase may facilitate the efflux of nitrite derived S-nitrosothiols from red blood cells

Redox Biology, 2013
Protein disulfide isomerase (PDI) is an abundant protein primarily found in the endoplasmic reticulum and also secreted into the blood by a variety of vascular cells.
Vasantha Madhuri Kallakunta, Anny Slama-Schwok, Bulent Mutus   +2 more
doaj   +1 more source

Effects of polydispersity on the glass transition dynamics of aqueous suspensions of soft spherical colloidal particles

, 2017
Thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) particles of a nearly constant swelling ratio and with polydispersity indices (PDIs) varying over a wide range (7.4% - 48.9%) are synthesized to study the effects of polydispersity on the dynamics of ...
Bandyopadhyay, Ranjini, Behera, Sanjay Kumar, Gadige, Paramesh, Saha, Debasish   +3 more
core   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

CONTRIBUIÇÕES DO PDI E DO PLANEJAMENTO ESTRATÉGICO NA GESTÃO DE UNIVERSIDADES FEDERAIS

Revista Gestão Universitária na América Latina, 2013
This article aims to analyze the contributions of the Institutional Development Plan and Strategic Planning in the management of Braz ilia n Federal U niversities, which carried out interviews and documentary analysis in eight federal universities : UFAL
Júlio Eduardo Ornelas Silva, Pedro Antônio de Melo, Alexandre Moraes Ramos, Cláudio José Amante, Flora Moritz da Silva   +4 more
doaj  

Reversal of Alpha-Synuclein Fibrillization by Protein Disulfide Isomerase

Frontiers in Cell and Developmental Biology, 2020
Aggregates of α-synuclein contribute to the etiology of Parkinson’s Disease. Protein disulfide isomerase (PDI), a chaperone and oxidoreductase, blocks the aggregation of α-synuclein.
Albert Serrano, Xin Qiao, Jason O. Matos, Lauren Farley, Lucia Cilenti, Bo Chen, Suren A. Tatulian, Ken Teter   +7 more
doaj   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

O IMPACTO DA ESTRUTURA LEGAL DO PDI NO PROCESSO DE PLANEJAMENTO ESTRATÉGICO DE INSTITUIÇÕES DO SISTEMA AMPESC

Revista Gestão Universitária na América Latina, 2011
Article contextualizing lecture on the impact of legal instruments related to the construction of the Institutional Development Plan (IDP) in the process of strategic planning system AMPESC institutions that are located in the southern state of Santa ...
Thiago Henrique Almino Francisco, Alexandre Moraes Ramos, Nilo Otani, Ângela Regina Heinzen Amin Helou, Expedito Michels,   +4 more
doaj