Results 171 to 180 of about 55,070 (279)

Testing for Genetic Interactions in Complex Disease With Distance Correlation

Biometrical Journal, Volume 68, Issue 5, October 2026.
ABSTRACT Understanding epistasis (genetic interaction) may shed some light on the genomic basis of common diseases, including disorders of maximum interest due to their high socioeconomic burden, like schizophrenia. Distance correlation is an association measure that characterizes general statistical independence between random variables, not only the ...
Fernando Castro‐Prado, Javier Costas, Dominic Edelmann, Wenceslao González‐Manteiga, David R. Penas   +4 more
wiley   +1 more source

Small investment, big returns: examining the effects of having a ‘Yellow Card’ on immunization and growth monitoring of young children in Lao PDR

Annals of Global Health, 2016
A. Mobasser, M. Fong, J. Bitzer, J. Measelle   +3 more
doaj   +1 more source

Topographical Evaluation of Neovessels in Proliferative Diabetic Retinopathy by Using a Multimodal Imaging Approach. [PDF]

J Clin Med
Costanzo E, Fenicia V, Giammaria S, Polito MS, Mecarelli G, Varano M, Parravano M.   +6 more
europepmc   +1 more source

Progressive Cognitive Decline and Pyramidal Signs in a Patient With a Novel Homozygous c.395A>T; p.Lys132Met Mutation in CHCHD2

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Biallelic CHCHD2 variants are rare. We report a consanguineous man with a novel homozygous CHCHD2 c.395A>T (p.Lys132Met) variant who developed progressive cognitive decline, apraxia, oculomotor impairment, and pyramidal signs without parkinsonism.
Mehri Salari, Arash Soltani, Masoud Etemadifar, Kamran Rezaei   +3 more
wiley   +1 more source

Structural and Functional Characterisation of a Metagenome‐Derived CYP108D18 Reveals an Unusual Dioxygen‐Bound State and Selective Hydrocarbon Hydroxylation

Microbial Biotechnology, Volume 19, Issue 10, October 2026.
CYP108D18, identified from a hot spring metagenome, catalyses selective phenylcyclohexane hydroxylation. This P450 has an exceptionally low substrate‐bound heme redox potential. Crystal structures revealed an unusual dioxygen‐bound substrate‐free form and a persistent open active site upon substrate binding.
Simran Kundral, Peter D. Giang, Alicia M. Kirk, Julia B. Buczynski, Kasun S. A. Arachchige, Sunil K. Khare, Paul V. Bernhardt, Paul N. Evans, Luke W. Guddat, Stephen G. Bell, James J. De Voss   +10 more
wiley   +1 more source

Clinical Outcomes of Pandrug-Resistant Versus Carbapenem-Resistant, Colistin-Susceptible <i>Acinetobacter baumannii</i> Infections: A Retrospective Analysis of a Prospective Multicentre Cohort. [PDF]

Antibiotics (Basel)
Karaiskos I, Daikos GL, Michelidou S, Mouratidou C, Gavala A, Gkoufa A, Sakagianni A, Mouloudi E, Tsigou E, Routsi C, Karakonstantis S, Stamatopoulou C, Markantonaki D, Veroniki F, Pirounaki M, Kyriakoudi A, Ampelioti S, Anastogiannis C, Koutsoukou A, Giamarellou H, Pontikis K.   +20 more
europepmc   +1 more source

Early Worsening of Diabetic Retinopathy Following Initiation of Hybrid Closed‐Loop/Automated Insulin Delivery Systems in Type 1 Diabetes: A Systematic Review and Structured Study‐Level Synthesis

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8878-8894, October 2026.
ABSTRACT Background Hybrid closed‐loop (HCL) systems achieve rapid, algorithm‐driven improvements in glycaemia in type 1 diabetes (T1D). Paradoxically, rapid improvement in glycaemic control is associated with early worsening of diabetic retinopathy (EWDR), a phenomenon established in the intensive insulin therapy era.
Matthew Anson, Ahmed Iqbal, Shazli Azmi, Philip Weston, Lucy Hughes, Mahreen Choudhury, David M. Hughes, Yalin Zheng, Philip I. Burgess, Uazman Alam   +9 more
wiley   +1 more source

Sympathetic ophthalmia complicating proliferative diabetic retinopathy: diagnostic and therapeutic challenges during pregnancy. [PDF]

BMC Ophthalmol
Alshabib N, Alarfaj M, Albahlal A, Alyousif NA.   +3 more
europepmc   +1 more source

Association of glycation gap with hypoglycemia CGM indices, diabetic complications, and quality of life in Japanese type 2 diabetes patients

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1794-1806, October 2026.
The difference between HbA1c and estimated A1c (eA1c) was defined as the GGap. The strong association of high GGap with CGM‐based hypoglycemic indices in type 2 diabetes is evident. The large GGap values, relying solely on HbA1c values during treatment, may increase the risk of hypoglycemia in patients with T2DM.
Satomi Sonoda, Yosuke Okada, Tomoya Mita, Keiichi Torimoto, Kenichi Tanaka, Fumiya Sato, Naoto Katakami, Hidenori Yoshii, Keiko Nishida, Shingo Nakayamada, Ryota Ishii, Masahiko Gosho, Iichiro Shimomura, Hirotaka Watada   +13 more
wiley   +1 more source

Construction and Validation of a Long-Term Visual Prognosis Prediction Model for Proliferative Diabetic Retinopathy After Vitrectomy Based on Machine Learning. [PDF]

Endocrinol Diabetes Metab
Wang X, Shi J, Gao Y, Li T, Han X, Guo L, Jia T, Wang Y.   +7 more
europepmc   +1 more source