Results 1 to 10 of about 79,931 (211)

Fighting Hypoxia to Improve PDT [PDF]

open access: yesPharmaceuticals, 2019
Photodynamic therapy (PDT) has drawn great interest in recent years mainly due to its low side effects and few drug resistances. Nevertheless, one of the issues of PDT is the need for oxygen to induce a photodynamic effect.
Régis Vanderesse   +2 more
exaly   +7 more sources

Molecular Design of Conjugated Small Molecule Nanoparticles for Synergistically Enhanced PTT/PDT

open access: yesNano-Micro Letters, 2020
A donor–acceptor–donor (D–A–D) conjugated small molecule IID-ThTPA with narrow singlet–triplet energy gap is synthesized via acceptor-oriented molecular design. IID-ThTPA nanoparticles exhibit not only competitive photothermal conversion efficiency (35.4%
Wei Shao, Daishun Ling, Fangyuan Li
exaly   +2 more sources

Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
To investigate the impact of mono- and di-β-galactose moieties in tumor uptake and photodynamic therapy (PDT) efficacy, HPPH [3-(1′-hexyloxy)ethyl-3-devinylpyropheophorobide-a], the meso pyropheophorbide-a [3-ethyl-3-devinyl-pyropheophorbide-a], and the ...
Mykhaylo Dukh   +9 more
doaj   +1 more source

Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

open access: yesTheranostics, 2022
Cancer immunotherapy has made tremendous clinical progress in advanced-stage malignancies. However, patients with various tumors exhibit a low response rate to immunotherapy because of a powerful immunosuppressive tumor microenvironment (TME) and ...
Bin Ji, Min-Jie Wei, Bin Yang
semanticscholar   +1 more source

Homologous targeting nanoparticles for enhanced PDT against osteosarcoma HOS cells and the related molecular mechanisms

open access: yesJournal of Nanobiotechnology, 2022
Background No prominent advancements in osteosarcoma (OS) treatment have been made in the past 20 years. Although photodynamic therapy (PDT) is an emerging technique for cancer therapy, the lack of targeted photosensitizers for OS treatment severely ...
Yang Wang   +11 more
semanticscholar   +1 more source

Photodynamic Therapy: The Imminent Milieu For Treating Oral Lesions [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Photodynamic therapy (PDT) is used in curative and palliative treatment of head and neck squamous cell carcinoma (HNSCC) and other oral lesions. Oral infections (such as mucosal and endodontic infections, periodontal diseases, caries, and peri ...
Neeta Mohanty   +4 more
doaj   +1 more source

Engineering naphthalimide-cyanine integrated near-infrared dye into ROS-responsive nanohybrids for tumor PDT/PTT/chemotherapy

open access: yesBioactive Materials, 2021
Photodynamic (PDT) and photothermal therapies (PTT) are emerging treatments for tumour ablation. Organic dyes such as porphyrin, chlorin, phthalocyanine, boron-dipyrromethene and cyanine are the clinically or preclinically used photosensitizer or ...
Tong-Xia Jin   +10 more
semanticscholar   +1 more source

Primary Aldosteronism: A Series of 11 Cases [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Primary Aldosteronism (PA) should be suspected in patients with resistant hypertension, early-onset hypertension, hypertension with hypokalaemia, and metabolic alkalosis.
Abhranil Dhar   +4 more
doaj   +1 more source

Polymethine dyes for PDT: recent advances and perspectives to drive future applications

open access: yesPhotochemical and Photobiological Sciences, 2022
It has been proved that the effectiveness of photodynamic therapy (PDT) is closely related to the intrinsic features of the photosensitizer (PS). Over the recent years, several efforts have been devoted to the discovery of novel and more efficient ...
D. Dereje   +4 more
semanticscholar   +1 more source

Solvothermal synthesis of rhombic shape GdF3:Tb3+ nanoparticles for biomedical applications

open access: yesЮжно-Российский онкологический журнал, 2023
Purpose of the study. In this work, we have investigated the mechanism of structure formation of GdF3:Tb3+(15 %) nanocrystals synthesized by solvothermal synthesis in the temperature range from RT to 200 °C with a step of 50 °C.Materials and methods ...
E. A. Kuchma   +5 more
doaj   +1 more source

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