Results 131 to 140 of about 17,950 (297)

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Energy storage configuration considering user-shared costs in peak shaving auxiliary services with improved multi-objective particle swarm optimization

AIP Advances
To enhance peak-shaving and valley-filling performance in residential microgrids while reducing the costs associated with energy storage systems, this paper selects retired power batteries as the storage solution, breaking through existing optimization ...
Yiyou Xing, Jin Shen, Xinru Li
doaj   +1 more source

Application and Economic Study on Deep Peak Shaving System for Coal-Fired Units Coupled with Non-Supplementary Compressed Air Energy Storage Technology

南方能源建设
[Objective] To enhance the deep peak shaving capacity of coal-fired units, this paper proposes a deep peak shaving system for coal-fired units coupled with non-supplementary compressed air energy storage.
Ting XU, Jingzheng HOU, Yuzhang ZHU, Chengwei LIU, Zhide ZHU, Yuchu LIU   +5 more
doaj   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

EOS: Impact Evaluation of Electric Vehicle Adoption on Peak Load Shaving Using Agent-Based Modeling

Energies
The increasing adoption of electric vehicles (EVs) by the general population creates an opportunity to deploy the energy storage capability of EVs for performing peak energy shaving in their households and ultimately in their neighborhood grid during ...
William J. Howell, Ziqian Dong, Roberto Rojas-Cessa   +2 more
doaj   +1 more source

A Wood Plasticine With Controlled Phase‐Change Behavior and Malleability for Energy‐Closed‐Loop and Conformally Adaptive Thermal Management

Advanced Science, EarlyView.
A photothermal wood plasticine exhibiting controlled phase‐change behavior and malleable property is developed. The developed wood plasticine can provide all‐day, on‐demand, and low‐loss solar heating for geometrically diverse objects, including thermoelectric generator, human body, and battery, through its controlled crystallization‐melting ...
Jiazuo Zhou, Yifan Liu, Lei Qiao, Yuehe Gu, Taikun Yao, Wenbo Zhang, Fangmiao Wang, Yudong Li, Xinyao Ji, Lingyi Kong, Haiyue Yang, Yao Xiao, Chengyu Wang   +12 more
wiley   +1 more source

Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement

Advanced Science, EarlyView.
This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen, Xinyu Shen, Hanning Liu, Lamei Du, Caicai Jiao, Longfei Li, Qian Wang, Qiuting Zhang, Lixue Tang, Liang Hu, Yubo Fan   +10 more
wiley   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source