Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano +20 more
wiley +1 more source
The peak shifting electricity consumption management and influencing factors of smart grid from recurrent neural network model and deep learning. [PDF]
Wang F, Huang D, Lu W.
europepmc +1 more source
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng +3 more
wiley +1 more source
Research Progress on the Stable Operation of Pulverized Coal-Fired Boilers under Low-Load Conditions. [PDF]
Cao H, Xu L, Zhang G, Cui Y, Zhang L.
europepmc +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Development of lightweight, environmentally friendly bricks using leather shaving and buffing dust waste. [PDF]
Mithu MR +4 more
europepmc +1 more source
Thermal Calculations for Co‐Firing of Hydrogen/Ammonia and Coal in 660‐MW Coal‐Fired Boilers
ABSTRACT To achieve a clean energy transition under the dual carbon goals, blending hydrogen/ammonia into pulverized coal boilers represents a key technological pathway. Different hydrogen/ammonia co‐firing ratios (5%–50%) are investigated for their impact on the thermodynamic characteristics of 660‐MW supercritical boiler at 100% and 20% boiler ...
Yaodong Da +7 more
wiley +1 more source
Synergistic Low-Carbon Economic Dispatch of a Virtual Power Plant with Microencapsulated Carbon Capture and Demand Response. [PDF]
Liu H, Lu H.
europepmc +1 more source
Quantitative assessment of masticatory muscles based on skull muscle attachment areas in Carnivora
Abstract Masticatory muscles are composed of the temporalis, masseter, and pterygoid muscles in mammals. Each muscle has a different origin on the skull and insertion on the mandible; thus, all masticatory muscles contract in different directions. Collecting in vivo data and directly measuring the masticatory muscles anatomically in various Carnivora ...
Kai Ito +4 more
wiley +1 more source
Managing the aftermath: complications and outcome after colorectal resection for deep infiltrating endometriosis-insights from a certified surgical endoscopy center. [PDF]
Flammang I +6 more
europepmc +1 more source

