Advanced Science, EarlyView.The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian +14 more
wiley +1 more source
OCPP integrated artificial intelligence for forecasting scheduling and anomaly detection in city scale electric vehicle charging under urban tariffs. [PDF]
Sci RepHossen MS +4 more
europepmc +1 more source
Advanced Science, EarlyView.Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang +4 more
wiley +1 more source
Divergence in surface protein exposure between reference and clinical-derived <i>Candida glabrata (Nakaseomyces glabratus)</i> strains (CBS138 vs. BG2) - a preliminary proteomic perspective. [PDF]
Acta Biochim PolBednarek A +5 more
europepmc +1 more source
Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits
Advanced Science, EarlyView.This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou +3 more
wiley +1 more source
Synergistic Low-Carbon Economic Dispatch of a Virtual Power Plant with Microencapsulated Carbon Capture and Demand Response. [PDF]
ACS OmegaLiu H, Lu H.
europepmc +1 more source
The Geography of Success: A Spatial Analysis of Export Intensity in the Italian Wine Industry
Agribusiness, EarlyView.ABSTRACT This paper investigates the paradox of how Italy's fragmented, SME‐dominated wine industry achieves global export success. Moving beyond purely firm‐centric explanations, we test whether export intensity is spatially dependent, clustering geographically in regional ecosystems.
Nicolas Depetris Chauvin, Jonas Di Vita
wiley +1 more source
Optimization and Comparative Study of Non-Pressurized Shell-and-Tube Latent Heat Storage for Air-Source Heat Pump Systems: Numerical and Experimental Investigation. [PDF]
Materials (Basel)Li W, Fu Y, Wang H, Zhang X.
europepmc +1 more source
AIChE Journal, EarlyView.Abstract The rapid growth of AI data centers (AIDCs) is intensifying stress on power systems and exposing operators to volatile electricity markets. This work develops a process‐informed co‐optimization framework that integrates liquid air energy storage (LAES) with AIDC operation. Unlike black‐box storage models, the proposed formulation captures LAES
Zhicong Fang +3 more
wiley +1 more source
Managing the aftermath: complications and outcome after colorectal resection for deep infiltrating endometriosis-insights from a certified surgical endoscopy center. [PDF]
Sci RepFlammang I +6 more
europepmc +1 more source