Results 221 to 230 of about 5,730,304 (286)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Reliable determination of chemical state in x-ray photoelectron spectroscopy based on sample-work-function referencing to adventitious carbon: Resolving the myth of apparent constant binding energy of the C 1s peak

Applied Surface Science, 2018
The accuracy of chemical-state determination by x-ray photoelectron spectroscopy (XPS) used in contemporary advanced materials research relies on a trustworthy binding energy (BE) referencing method.
Grzegorz Greczynski, Lars Hultman
exaly   +2 more sources

Modeling of analytical peaks: Peaks properties and basic peak functions

Analytica Chimica Acta, 2006
The general approach to the detailed characterizing of peak properties based on the use of characteristic points on a peak contour located at the certain levels is proposed. Three basic functions of peaks have been chosen which are submitted in normalized form on height and width. The ability to characterize a peaks shape of a certain analytical series
S V, Romanenko   +2 more
openaire   +2 more sources

CONTROL OF COMPLEX PEAK-TO-PEAK DYNAMICS

International Journal of Bifurcation and Chaos, 2002
The paper illustrates a method for the design of suitable controllers of chaotic systems characterized by complex peak-to-peak dynamics, namely by a recursive relationship between consecutive peaks (relative maxima) of a scalar output variable. For such systems, a reduced model can be defined which, in general, is a hybrid model composed of a one ...
PICCARDI, CARLO, RINALDI, SERGIO
openaire   +4 more sources

PEAK-TO-PEAK DYNAMICS: A CRITICAL SURVEY

International Journal of Bifurcation and Chaos, 2000
This paper is devoted to the study of a particular form of deterministic chaos, here called peak-to-peak dynamics (PPD). When a continuous-time system of order n has PPD, the amplitude and the time of occurrence of the next peak of its output variable can be predicted from information concerning at most two previous peaks.
M. Candaten, RINALDI, SERGIO
openaire   +2 more sources

Peak Oil, Peak Water, Peak Education

New Directions for Teaching and Learning, 2013
AbstractThis chapter argues that today's dominant forms of education are insufficient for today's world because they ignore the vast and conventionally untapped resource that lies in the disciplined inwardness that is contemplative life. It then surveys a range of transformative examples that are emerging in the educational movement known as ...
openaire   +1 more source

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