Results 61 to 70 of about 5,771,017 (249)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Pattern recognition residential demand response: An option for critical peak demand reduction [PDF]

open access: yes, 2010
Influencing households to adopt sustainable energy consumption behaviour is important to the transition towards a sustainable energy future. However, if one aims at influencing the energy consumption habits of people, one should also be able to estimate ...
Krumdieck, S., Gyamfi, S., Brackney, L.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An Innovative Adaptive Threshold-Based BESS Controller Utilizing Deep Learning Forecast for Peak Demand Reductions

open access: yesIEEE Access
Battery-based energy storage systems (BESS) can be installed and controlled by a control strategy to reduce daily peak demands. Majority of the existing controllers for BESS is developed and studied on a simulation platform. Hence, an innovative adaptive
MD Mahmudul Hasan   +7 more
doaj   +1 more source

Peak Power Reduction Strategies for the Lighting Systems in Government Buildings [PDF]

open access: yes, 2010
Lighting systems are the second major contributor to the peak power demand and energy consumption in buildings after A/C systems. They account for nearly 20% of the peak power demand and 15% of the annual energy consumption.
Al-Nakib, D.   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Demand Flexibility of Pre-Cooling Strategies for City-Scale Buildings Through Urban Building Energy Modeling

open access: yesBuildings
With the increasing demand for electricity, it is causing a growing burden on the power grid. In order to alleviate the pressure on the power system, a series of demand response (DR) strategies have emerged. This paper studied the DR potential and energy
Anni Xu   +3 more
doaj   +1 more source

Optimized Scheduling of EV Charging in Solar Parking Lots for Local Peak Reduction under EV Demand Uncertainty

open access: yesEnergies, 2020
Scheduled charging offers the potential for electric vehicles (EVs) to use renewable energy more efficiently, lowering costs and improving the stability of the electricity grid.
Rishabh Ghotge   +4 more
doaj   +1 more source

Changing demand: flexibility of energy practices in households with children (interim report) [PDF]

open access: yes, 2014
This report investigates the practices that use energy in households with children to understand change and flexibility for demand management. The findings suggest that demand management and engagement activities need to go beyond individually motivating
Yolande Strengers, Larissa Nicholls
core  

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