Results 91 to 100 of about 1,566,640 (302)

Colloidal Dynamics on Disordered Substrates

, 2001
Using Langevin simulations we examine driven colloids interacting with quenched disorder. For weak substrates the colloids form an ordered state and depin elastically. For increasing substrate strength we find a sharp crossover to inhomogeneous depinning
A. Pertsinidis, A. Tonomura, C. J. Olson, C. Reichhardt, K-H. Lin, P. Korda, P. LeDoussal   +6 more
core   +1 more source

Maximal isometric and eccentric hamstring strength is influenced by body mass and additional load: Does the critical point at which peak knee flexor force is achieved play a role?

Frontiers in Physiology
Isometric (ISO) and eccentric (ECC) hamstring tests are used to assess peak force at various knee angles. However, it is unknown to what extent body weight influences the so-called “critical point” at which individuals achieve their maximal knee flexor ...
Andrew Rinaldi Sinulingga, Andrew Rinaldi Sinulingga, Andrew Rinaldi Sinulingga, Erika Zemková   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development of Improved Confined Compression Testing Setups for Use in Stress Relaxation Testing of Viscoelastic Biomaterials

Gels
The development of cell-based biomaterial alternatives holds significant promise in tissue engineering applications, but it requires accurate mechanical assessment.
Anthony El Kommos, Alicia R. Jackson, Fotios Andreopoulos, Francesco Travascio   +3 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Hydraulic servo system increases accuracy in fatigue testing [PDF]

, 1967
Hydraulic servo system increases accuracy in applying fatigue loading to a specimen under test. An error sensing electronic control loop, coupled to the hydraulic proportional closed loop cyclic force generator, provides an accurately controlled peak ...
Dixon, G. V., Kibler, K. S.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Effect of exercise-induced arterial hypoxemia on quadriceps muscle fatigue in healthy humans [PDF]

, 2006
The effect of exercise-induced arterial hypoxemia (EIAH) on quadriceps muscle fatigue was assessed in 11 male endurance-trained subjects [peak O2 uptake (V̇o2 peak) = 56.4 ± 2.8 ml·kg−1·min−1; mean ± SE]. Subjects exercised on a cycle ergometer at ≥90% V̇
Dempsey, JA, Haverkamp, HC, Lovering, AT, Pegelow, DF, Romer, LM   +4 more
core   +1 more source

Frequency and Resting Time Dependencies of Electrically-Induced Muscle Contraction Force

Journal of Biomechanical Science and Engineering, 2009
Physical exercise is a promising countermeasure for osteoporosis and strengthens skeletal muscle as well, resulting in a reduction of the risk of fall.
Shigeo M. TANAKA, Kanako KONDO
doaj   +1 more source