Results 171 to 180 of about 495,930 (304)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

High frequency acousto-electric microsensors for liquid analysis [PDF]

Liquid sensors are required for a multitude of applications in the food and beverage sectors, in the pharmaceutical industry or environmental monitoring.
Leonte, Irina Ionela
core  

Comprehensive Determination of Lipid Peroxidation Biomarkers in Ovine Tissues and Plant Oils by C18-UHPLC-DAD and GC-FID. [PDF]

Molecules
Czauderna M, Białek M, Wojtak W, Białek A, Fesenko V.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Impact of simulated gastric acid on electrochemical behavior, surface morphology, and topography of 3D printed cobalt chromium and titanium alloys for dental applications. [PDF]

BMC Oral Health
El-Tamimi KM, Bayoumi DA, Ahmed MMZ, Habba MIA, Zahra SE, El-Sayed ME.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Simultaneous bioanalytical method development and validation of ibuprofen and phenyramidol HCl in human plasma using high-performance liquid chromatography with photodiode array detection and its application in a pharmacokinetic study. [PDF]

J Chromatogr Sci
Kızıltas N, Akman TC, Karabayir Y.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Problem Solving During Peak and Non-Peak Circadian Arousal

, 2015
The aim of our project was to examine variables that inhibit or augment creative thinking about personal social problems. Prior research indicates that types of information processing strategies adopted by people vary as a function of circadian arousal ...
Rhoads, Erin
core  

Effect of a magnetic field on the activity of superoxide dismutase studied at the enzyme level. [PDF]

RSC Adv
Yoon S, Chang SC, Payne GF, Lee S, Kyhm K, Park SG, Kang M.   +6 more
europepmc   +1 more source