Results 221 to 230 of about 495,930 (304)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Sensitive stripping voltammetric determination of an anthracene-isatin Schiff base in biological samples. [PDF]

Turk J Chem
Öztürk G, Gökgöz İ, Arslan E, Şişman E, Doğan İS, Kul D, Ağin F.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Luminescent Wearable Sensor on Anions from Cotton Fabric Grafted with Cu-In-Zn-S Colloidal Quantum Dots. [PDF]

Sensors (Basel)
Liu X, Zhu P, Ren H, Wang Y, Li J, Zhang Y, Wang Q, Lee SW, Belfiore LA, Artemyev M, Tang J.   +10 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Tailoring crystallization kinetics for scalable and efficient large-area perovskite light-emitting diodes. [PDF]

Sci Adv
Baek SD, Tang Y, Choi H, Jiang S, Hu Q, Yang YT, Yang H, Xu W, Yoon K, Drolia D, Wang L, Joy S, Jeong SH, Lee G, Narsimhan V, Graham KR, Miller JT, Mei J, Lee YH, Dou L.   +19 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Combined spectroscopic and microscopic investigation of stability upon atmospheric exposure of Ag nanoparticle solutions produced by sputtering onto rapeseed oil. [PDF]

Nanoscale Adv
Lasfargues H, Ramesh DJ, Freymann LC, Schneider JM, Azina C.   +4 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Improved Source Localization of Auditory Evoked Fields using Reciprocal BEM-FMM. [PDF]

Brain Topogr
Drumm DA, Ponasso GN, Linke A, Ganguly S, Wang A, Noetscher GM, Maess B, Knösche TR, Haueisen J, Lewine JD, Abbott CC, Makaroff SN, Deng ZD.   +12 more
europepmc   +1 more source