Results 101 to 110 of about 123,863 (280)

An Impossible Utopia: People’s Art and the Cultural Revolution

open access: yes, 2014
The Great Proletarian Cultural Revolution period of the People’s Republic of China (1966-1976) was crucial in the creation of modern-day China. The material culture of that period mirrors the turbulent political activity of students and the directives of
Reynolds, Molly E.
core   +1 more source

The agrarian question in Tanzania: the case of tobacco [PDF]

open access: yes, 1980
African Studies Center Working Paper No. 32Since independence in 1961, Tanzania has pursued a policy of institutionalizing a middle peasantry, while stymieing the development of capitalism's principal classes.
Mueller, Susanne D.
core  

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao   +11 more
wiley   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

open access: yesAdvanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai   +6 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Agricultural Policy, Crop Failure and the 'Ruriganiza' Famine (1989) in Southern Rwanda: a Prelude to Genocide ? [PDF]

open access: yes
The paper analyses the agricultural policy of the Habyarimana regime, which ruled Rwanda from 1973 to 1994. Econometric analysis of rural household survey data is used to investigate the effects of the 1989 crop failure in southern Rwanda on children’s ...
Philip Verwimp
core  

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

open access: yesAdvanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo   +8 more
wiley   +1 more source

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

open access: yesAdvanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi   +15 more
wiley   +1 more source

Morality and institutions: an exploration [PDF]

open access: yes, 2008
This paper explores the question of how culturally varying views of ‘morality’, ‘fairness’ and ‘justice’, particularly those held by the rural poor in developing countries, influence the way people evaluate,work within, use and (sometimes) resist ...
Morton, John F.
core  

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