Results 151 to 160 of about 123,863 (280)

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Factors associated with modern contraceptive utilization among postpartum adolescent girls and young women in rural Mara, Tanzania: facility-based cross-sectional study. [PDF]

Ther Adv Reprod Health
Sichalwe MM, Tavengana G, Behera MR, Haq FU, Egbobe JO, Ullah S, Kimaro RR, Basit A.   +7 more
europepmc   +1 more source

Cluster‐Mediated Solute Stabilization and Shear‐Bypass Synergistic Strengthening in High‐Alloyed Systems

Advanced Science, EarlyView.
This study demonstrates that in high‐alloy systems, nanoclusters with high solute tolerance can effectively suppress compositional segregation. This mitigation leads to a concurrent 18.7% increase in strength and 41.5% improvement in ductility, which is attributed to a shear‐bypass synergistic strengthening mechanism. The findings provide a new pathway
Wei Yu, Yu Bai, Jiawen Li, Kaixi Jiang, Hai Hao, Tao Jiang, Shunan Zhang, Yong Li, Zhaodong Wang, Kai Zhao, Shiwei Li   +10 more
wiley   +1 more source

Knowledge, Attitude, and Practices to Foodborne Zoonotic Diseases and Their Associated Factors in and Around Debre Tabor City, Northwest Ethiopia. [PDF]

Vet Med Int
Abebaw B, Assefie S.
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Delayed completion of pneumococcal conjugate vaccination among children 4-48 months in rural Uganda: a socio-demographic inquiry. [PDF]

BMC Pediatr
Malemo H, Tamale A, Kakwangire P, Igwe MC, Mwine DR, Asiimwe I, Mbina SA, Abalinda MG.   +7 more
europepmc   +1 more source

AID AND AGENCY IN AFRICA EXPLAINING FOOD DISBURSEMENTS ACROSS ETHIOPIAN HOUSEHOLDS, 1994-2004. [PDF]

We study the distribution of food aid in Ethiopia between 1994 and 2004 using data from the Ethiopian Rural Household Survey. Over this period village leaders had considerable discretion in disbursing aid subject to official guidelines and periodic ...
NZINGA H. BROUSSARD, ROHINI SOMANATHAN, STEFAN DERCON   +2 more
core  

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Lev Tolstoy, A Founder of Democratic Education. [PDF]

Integr Psychol Behav Sci
Matusov E.
europepmc   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source