Results 91 to 100 of about 49,387 (257)

Scientific and methodological support for socialization of teenage mothers in the specialized agencies [PDF]

Психологическая наука и образование (2007. Online), 2014
The paper deals with the issues that arise in solving problems of socialization of teenage mothers. The article is based on an analysis of the activities of the specialized agencies, in which minor expectant mothers from fourteen years, and teenage ...
V.G. Mikhailovsky, V.A. Pestov
doaj  

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Pedagogical Experiment and Modeling of the Learning Process for Assessing Knowledge about the Criteria Assessment System

Qubahan Academic Journal
This article addresses the need for criterion-based evaluation in educational reform, focusing on the goals and tasks of planning in the updated educational system.
Sagyngali Kalkashev , Gaisin Ilgizar , Bakhadurkhan Abdimanapov , Nurbol Ussenov , Aliya Ayapbekova , Kuralai Khamitova   +5 more
doaj   +1 more source

MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion

Advanced Science, EarlyView.
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong, Ji Ma, Yidan Lu, Jiahui Zhang, Wanyue Li, Yeke Chen, Teng Zhang, Xuechao Chen, Zhangguo Yu, Peng Lu   +9 more
wiley   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

THE INFLUENCE OF GENDER AND AGE FACTORS ON THE FORMATION OF PROFESSIONAL SELF-IDENTITY OF FUTURE TEACHERS

Неперервна професійна освіта: теорія та практика
This article is a continuation of a series of works devoted to the study of the perceptions of higher education students who plan to work in the “human-human” system regarding the personal qualities of a professional in the chosen field.
Yurii Zhuk , Mykola Holovko , Svitlana Holovko , Svitlana Naumenko   +3 more
doaj   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

Advanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

Gendered Challenges in Academia: Exploring the Impact of Working Hours, Stress, and Job Satisfaction Among Mid-Level University Staff in Germany

Education Sciences
This study examines the relationships between job satisfaction, overtime hours, perceived stressors, and burnout symptoms among academic mid-level staff at German universities, with a particular focus on gender differences.
Heinke Röbken, Nicole Geier, Dorthe Behrens, Anne Mertens   +3 more
doaj   +1 more source