Results 191 to 200 of about 10,407 (258)

Hybridization of molecules via a common photonic mode. [PDF]

Proc Natl Acad Sci U S A
Nobakht J, Pscherer A, Renger J, Götzinger S, Sandoghdar V.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Impaired envelope integrity in the absence of SanA is linked to increased lipid II availability and an imbalance of septal peptidoglycan synthesis. [PDF]

mBio
Carr JF, Basurto De Santiago C, Bhut SA, Warzecha DJ, Vastani SA, Wei R, Herrera CM, Trent MS, Nan B, Mitchell AM.   +9 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Simulation and kinematic analysis of a 3-DOF marine antenna pedestal focusing on singularity avoidance and its effects on angular velocity and angular acceleration. [PDF]

Sci Rep
GholamiOmali A, Alizadeh M, Sadedel M.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Early-term clinical and radiographic outcomes of a new short cementless stem for primary total hip arthroplasty in young and active patients. [PDF]

J Exp Orthop
Minelli M, Longobardi V, Rosolani M, D'Addona A, Di Francia VP, Andreotti M, Madonna G, Della Rocca F.   +7 more
europepmc   +1 more source

Coral growth records 20^th Century sea-level acceleration and climatic variability in the Indian Ocean. [PDF]

Nat Commun
Kench PS, Morgan KM, Owen SD, Lin K, Wang X, Ramos RD.   +5 more
europepmc   +1 more source

Electrophysiological evidence of Hebbian plasticity in awake adult rats. [PDF]

J Neurophysiol
Gaikwad SS, Chen Y, Chen B, Bogue WHD, Scesa G, Neehouse MS, Vaughan TM, Carp JS, Oudega M, Wolpaw JR, Perez MA.   +10 more
europepmc   +1 more source

Quantitative Characterization of Corneal Collagen Architecture Using Intensity Gradient Modeling and Gaussian PDF Fitting. [PDF]

Diagnostics (Basel)
Fernandez EJ, Bueno JM.
europepmc   +1 more source