Results 171 to 180 of about 69,287 (288)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Convergent mechanisms of epithelial cell structure manipulation by intestinal pathogens. [PDF]

PLoS Pathog
Rodrigues E, Marzook NB, Pallett MA, Sateriale A.   +3 more
europepmc   +1 more source

2191) Fbw Comments on Pedestal Pile(Structure)

Transactions of the Architectural Institute of Japan, 1963
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Glaucoma Classification Through SSVEP-Derived ON- and OFF-Pathway Features. [PDF]

Transl Vis Sci Technol
Scott MTW, Xu H, Yakovleva A, Tibshirani R, Goldberg JL, Norcia AM.   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

When does turbulence spreading matter? [PDF]

, 2020
Diamond, PH, Singh, Rameswar
core  

Taming harmful bursts and heat flux in high-confinement tokamak plasmas. [PDF]

Nat Commun
Hu QM, Wang HQ, Navarro M, Wang HH, Eldon D, Gu S, Ma XX, Frerichs H, Scotti F, Wang L, Wilcox RS, Wilks TM, Bortolon A, Ceelen L, Effenberg F, Gong XZ, Jia MN, Kim SK, Lasnier CJ, Leonard AW, Li KD, Logan NC, Ma Q, Maingi R, Meng LY, Moser AL, Osborne TH, Paz-Soldan C, Shafer MW, Sun YW, Yang SM, Ye C.   +31 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

A global view of morphogenetic peptidoglycan synthases across the domain Bacteria. [PDF]

Microlife
García-Del Portillo F, López-Escarpa D, Peñalver M, Castanheira S.   +3 more
europepmc   +1 more source