Results 161 to 170 of about 5,846 (225)

Muscle Weakness and the Irisin–BDNF and Oxidative Stress Axis in the 60‐Day Pseudorandomised Controlled AGBRESA Bed Rest Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Muscle atrophy and weakness are among the most detrimental consequences of disuse, microgravity, hospitalisation and ageing. Oxidative modifications of myofibrillar proteins generated by oxidative stress may contribute to the reduced force‐ and power‐generating capacity of skeletal muscles. As part of the 60‐day AGBRESA bed rest (BR)
Alessandra Bosutti   +10 more
wiley   +1 more source

PDXK‐Related Neuropathy: A Case With a Novel Splice‐Altering Missense Variant and Literature Review

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
We report a patient carrying a novel missense variant c.826G>C, p.(Ala276Pro) found in compound heterozygous state with a previously reported variant in the PDXK gene. In silico analysis and our functional studies showed that the novel variant disrupts splicing, which leads to degradation of the aberrant transcript, thereby extending the known disease ...
Dmitrii Subbotin   +7 more
wiley   +1 more source

STUDY OF PEDESTRIAN-INDUCED VIBRATIONS ON TIMBER FOOTBRIDGESC

open access: yesMaderas: Ciencia y Tecnología, 2010
P. G. A Segundinho
doaj  

Rubber Tube–Based Triboelectric Nanogenerator for Simultaneous Energy Harvesting and Real‐Time Health Monitoring in Taekwondo Athletes

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
A flexible P(AA‐MA)‐PVA hydrogel‐based triboelectric nanogenerator (PP‐TENG) efficiently harvests biomechanical energy and enables self‐powered tennis motion sensing. The device integrates high stretchability, self‐healing, and polydimethylsiloxane protection, achieving 182 V output and real‐time multi‐joint monitoring for intelligent sports analysis ...
Chengquan Piao   +3 more
wiley   +1 more source

MiR‐210‐3p is upregulated in diabetic peripheral neuropathy and may be involved in the progression of the disease by targeting brain‐derived neurotrophic factor

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 4, Page 672-680, April 2026.
Elevated miR‐210‐3p expression was diagnostic for diabetic peripheral neuropathy (DPN) and served as an independent risk factor for DPN. miR‐210‐3p functioned by negatively regulating BDNF, and its inhibitor reversed hyperglycemia‐induced Schwann cell dysfunction, whereas BDNF knockdown eliminated this protective effect.
Yafei Zhao, Liu Wang, Dongcai Feng
wiley   +1 more source

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