Results 51 to 60 of about 22,459 (117)
A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development
Advanced Science, Volume 13, Issue 47, 24 August 2026.SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu +33 morewiley +1 more sourcePediatric epilepsy surgery: Global survey of referral and presurgical evaluation practices
Epilepsia, Volume 67, Issue 8, Page 4008-4024, August 2026.Abstract Objective
Pediatric epilepsy surgery is well established, but contemporary global data on referral and presurgical evaluation practices are lacking. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Task Force study provides an updated overview of current trends and regional differences. Methods
Group‐level data were Georgia Ramantani, J. Helen Cross, Dorottya Cserpan, Emtnan Ahemad, Javier Aparicio, Alexis Arzimanoglou, Carmen Barba, William Bingaman, Kees Braun, Richard J. Burman, James Butler, Lixin Cai, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, Arthur Cukiert, Cristine Mella Cukiert, Sameer Dal, Dario Englot, Noelle Enright, Aria Fallah, Sarah Ferrand Sorbets, Martha Feucht, Deepak Gill, Laura Guio Mahecha, Aris Hadjinicolaou, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Yuwu Jiang, Lakshminarayanan Kannan, Kalman A. Katlowitz, Katarzyna Kotulska‐Jóźwiak, Martin Kudr, Matt Lallas, Ahsan Moosa Naduvil Valappil, Sandeep Bhagwan Patil, Tom Pieper, Nicola Specchio, Manjari Tripathi, Lejla Vendegh, Howard Weiner, Jo Wilmshurst, Mary Lou Smith, Elaine Wirrell, ILAE Pediatric Epilepsy Surgery Task Force and Study Group, Fabrice Bartolomei, Juan Carlos Benedetti Isaac, Poodipedi Sarat Chandra, Mary Connoly, Daniel Curry, Vicki Deli‐Peri, Luca De Palma, Nabeel Diab, Petia Dimova, Carolina Munoz Castro, Georg Dorfmüller, Jana Domínguez, Gianluca D'Onofrio, Christin Eltze, Johannes M. Nico Enslin, András Fogarasi, Siby Gopinath, Renzo Guerrini, Giulia Nobile, Masaki Iwasaki, Sita Jayalakshmi, Takayuki Kikuchi, Noritsugu Kunihiro, Paweł Kowalczyk, Niklaus Krayenbühl, Pavel Kršek, Thilo Kalbhenn, Kensuke Kawai, Cassia Maniquis, Wim Otte, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Catherine Riney, Jonathan Roth, Sabine Rona, Karl Rössler, Olga Teo, Oana Tarta Arsene, Laura Tassi, Hartlieb Till, T S Dhanya, Catalina Soto Órdenes, Piradee Suwanpakdee, Steffen Syrbe, Nigel Peter Symss, Jay Shetty, Dilşad Türkdoğan, Takehiro Uda, Naotaka Usui, Vrajesh Udani, Jithangi Wanigasinghe, Yi Wang +98 morewiley +1 more sourceTargeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice
Aging Cell, Volume 25, Issue 8, August 2026.Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.Sandra Freitas‐Rodríguez, Alejandra Valle‐Cao, Francisco Rodríguez, Manuel Fernández‐Sanjurjo, Benjamín Fernández‐García, Vanessa Loredo, María Teresa Fernández‐García, Carmen Fiuza‐Luces, Alejandro Lucia, Carlos López‐Otín, Alejandro López‐Soto, Alicia R. Folgueras +11 morewiley +1 more sourceGeneralidades de los estudios de casos y controles
Acta Pediátrica de México, 2018 ANTECEDENTES: los estudios de casos y controles son de utilidad cuando se buscan factores de riesgo para enfermedades poco comunes o que tienen un periodo de latencia prologado.
OBJETIVO: identificar las principales características del estudio de casos Alejandro González Garay, Luisa Díaz García, Chiharu Murata, Anahí Anzo Osorio, Silvestre García de la Puente +4 moredoaj +1 more sourceThe International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria
Allergy, Volume 81, Issue 8, Page 2582-2632, August 2026.ABSTRACT
This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...Torsten Zuberbier, Zainab AbdulHameed Ansari, Amir H. Abdul Latiff, M. M. Abuzakouk, Maria Socorro Agcaoili‐De Jesus, Rosana C. Agondi, Mona Al‐Ahmad, Abdullah A. Alangari, H. Alhameli, Cesar D. Alonso Bello, Saad Alshareef, Salem Al‐Tamemi, Sabine Altrichter, Humaid Al Wahshi, S. Aquilina, M. Araújo, Rand Arnaout, Riccardo Asero, Barbara Ballmer‐Weber, Christine Bangert, Andrea Bauer, Moshe Ben‐Shoshan, Jonathan A. Bernstein, Carsten Bindslev‐Jensen, Mojca Bizjak, Isabelle Boccon‐Gibod, Hanna Bonnekoh, Laurence Bouillet, Knut Brockow, Zenon Brzoza, M. Bulatović Ćalasan, Adeeb Bulkhi, Thomas Buttgereit, Anette Bygum, Teresa Caballero, Oscar Calderon, R. Campos, Mauro Cancian, Emily Carne, Mary Anne Castor, Inmaculada Cerecedo, T. Çetinarslan, Ivan Cherrez‐Ojeda, N. Chkhikvadze, Herberto J. Chong‐Neto, Karen Choo, George Christoff, Chia‐Yu Chu, K. Ciupka, Niall Conlon, Célia Costa, Timothy J Craig, Paulo Criado, Inna Danilycheva, Razvigor Darlenski, Erika De Arruda Chaves, Laurence de Montjoye, M.‐S. Doutre, Aurelie Du‐Thanh, Didier Ebo, S. Elkhalifa, S. Elmariah, Tariq El‐Shanawany, Luis F. Ensina, Ragip Ertaş, Roberta Fachini Jardim Criado, Marta Ferrer, Silvia Ferrucci, Jie Shen Fok, Daria Fomina, Luz Fonacier, Ghada Fouda, I. Francescantonio, Atsushi Fukunaga, César A. Galvan Calle, Elizabeth Garcia, Krisztian Gáspár, Aslı Gelincik, Songmei Geng, Kiran Godse, Margarida Gonçalo, Maia Gotua, C. Grattan, Martine Grosber, Guillermo Guidos Fogelbach, Mar Guilarte, R. Guillod, Eckard Hamelmann, Jason Hawkes, Koremasa Hayama, Ruben Heuer, Michihiro Hide, Wolfram Hoetzenecker, Naoko Inomata, Hye‐Ryun Kang, Allen P. Kaplan, Alexander Kapp, M. Karam, Alicja Kasperska‐Zajac, Constance H. Katelaris, Aharon Kessel, Maryam Khoshkhui, Brian Kim, Tamar Kinaciyan, Emek Kocatürk, Marta Kolacinska‐Flont, Pavel Kolkhir, George N. Konstantinou, Mitja Kosnik, Dorota Krasowska, Kanokvalai Kulthanan, Muthu S. Kumaran, Izabela Kuprys‐Lipinska, Moisés Labrador, Jose Ignacio Larco, Désirée Larenas‐Linnemann, Elena Latysheva, E. Lazaridou, Philip H. Li, H. Lima, Undine Lippert, Markus Magerl, Michael Makris, João Alves Marcelino, Angelo V. Marzano, Iris Medina, Raisa Meshkova, D. Micallef, Ramzy Mohammed Ali, Charlotte G. Mortz, Melba Munoz, Hanneke N. G. Oude Elberink, Alla Nakonechna, Iman Nasr, Alexander Nast, Elena Netchiporouk, Eustachio Nettis, Sandra Nieto, Isabel Ogueta Canales, T.‐L. Okas, Raquel L. Orfali, Esen Özkaya, Claudio Parisi, A. Pennitz, Ruby Pawankar, Manuel P. Pereira, Jonny Peter, Elena Petkova, P. D. Pigatto, Indrashis Podder, T. Popov, Grzegorz Porebski, Polina Pyatilova, German D. Ramon, Hector A. Ratti Sisa, Marysia Stella Recto, Krista Ress, Katie Ridge, Marc Riedl, Carla Ritchie, Nelson Rosario Filho, Isabel Rosmaninho, Michael Rudenko, Maia Rukhadze, Krzysztof Rutkowski, Vito Sabato, Umit M. Sahiner, Sarbjit Saini, F. Saleh Al Sabbagh, Andac Salman, Fulvio Salvo, Jorge Sanchez, A. Santucci, Sibylle Schliemann, Peter Schmid‐Grendelmeier, Bulent E. Sekerel, Faradiba Serpa, Farrukh Sheikh, J. Sheikh, H. Shendi, Frank Siebenhaar, M. Sonomjamts, Angele Soria, Bernardo Sousa Pinto, Maria Staevska, Petra Staubach, M. Stephan, Katarina Stevanovic, Luca Stingeni, Marcin Stobiecki, Özlem Su Küçük, Gordon Sussman, Andrea Szegedi, Shunsuke Takahagi, Akio Tanaka, Natasa Teovska Mitrevska, Simon Francis Thomsen, Elias Toubi, Fragkiski Tsatsou, Murat Turk, Zahava Vadasz, Anna Valerieva, Solange Valle, Martijn van Doorn, Beatriz Veleiro Perez, Carolina E. Vera Ayala, Christian Vestergaard, Rafael J. Vieira, C. W. Maruta, Bettina Wedi, Ricardo N. Werner, Evelyn Wen Yee Yap, Paraskevi Xepapadaki, Yi‐Kui Xiang, Young‐Min Ye, Patrick Yong, Gil Yosipovitch, Anna Zalewska‐Janowska, Christoph Zeyen, Zuotao Zhao, Martin Metz, Ana M. Giménez‐Arnau +221 morewiley +1 more source
