Results 141 to 150 of about 2,078,105 (245)

Serotype distribution and antibiotic susceptibility of Streptococcus pneumoniae strains in the south of Tunisia: A five-year study (2012–2016) of pediatric and adult populations

, 2017
Sonia Ktari, Ikram Jmal, Manel Mroua, Sonda Maalej, Nour ElHouda Ben Ayed, Basma Mnif, Faouzia Rhimi, Adnène Hammami   +7 more
openalex   +1 more source

Outcomes of infants with severe bronchopulmonary dysplasia in the pediatric intensive care unit [PDF]

, 2020
Yu Hyeon Choi, Hong Yul An, You Sun Kim, June Dong Park   +3 more
openalex   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Advanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong   +10 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals ITGA2‐Mediated Metabolic Reprogramming and Immune Crosstalk in Pediatric Thyroid Carcinogenesis

Advanced Science, EarlyView.
This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan, Ning Li, Yan Sun, Lu Chen, Jun‐da Yin, Yun‐han Shan, Jia‐xing Zeng, Zhe‐cheng Li, Hai‐long Tan, Neng Tang, Shi Chang, Peng Huang   +11 more
wiley   +1 more source

Age and trauma center-specific disparities in splenectomy rates for pediatric trauma patients. [PDF]

Trauma Surg Acute Care Open
Cain-Trivette CJ, Manin E, An A, Vitberg YM, Oh PS, Steigman S.   +5 more
europepmc   +1 more source

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

Nurses' perceptions of end-of-life care in neonatal and pediatric intensive care units in Korea: a qualitative descriptive study using thematic analysis. [PDF]

Child Health Nurs Res
Lee HJ, Kim H.
europepmc   +1 more source

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

Advanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng, Hua Wang, Li Zhang, Shiping Li, Yuan Yuan, Mengting Tian, Yi Qu, Junjie Ying, Meicen Zhou, Yong Hu, Jinglan Huang, Rong Zou, Fengyan Zhao, Xiaojuan Su, Qian Liu, Yan He, Jinxing Feng, Weimin Huang, Ying Luo, Zhemin Zhou, Wei Shen, Dezhi Mu, Shaopu Wang   +22 more
wiley   +1 more source

Toward governance of artificial intelligence in pediatric healthcare. [PDF]

NPJ Digit Med
Richter F, Holmes E, Richter F, Guttmann K, Duong SQ, Gangadharan S, Schadt EE, Salmasian H, Gelb BD, Glicksberg BS.   +9 more
europepmc   +1 more source

Pediatric dental care: prevention and management protocols based on caries risk assessment.

, 2010
Francisco Ramos‐Gomez, Yasmi O. Crystal, Man Wai Ng, James J. Crall, J.D.B. Featherstone   +4 more
openalex   +1 more source