Results 171 to 180 of about 2,171,498 (340)
Laboratory Manual of Pediatric Micro- and Ultramicro-biochemical Techniques [PDF]
Donough OʼBrien, Frank A. Ibbott
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Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka+5 more
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Rectal Use of Pentothal?? As Basal Hypnotic in Pediatric Surgery.
W. Migdal+2 more
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Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue+3 more
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Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
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This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao+21 more
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Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li+16 more
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A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran+25 more
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