Results 101 to 110 of about 683,524 (293)

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Management of pediatric airway granular cell tumor: Role of laryngotracheal reconstruction

, 2006
To discuss the role of laryngotracheal reconstruction (LTR) in granular cell tumor (GCT) and to highlight the importance and seriousness of GCT in pediatric airway cases.
Lehman, David A, Robinson, Philip G, Pernas, Francisco G, Younis, Ramzi T   +3 more
core   +1 more source

Advances in New Approach Methodologies at FDA's Division of Applied Regulatory Science

Clinical Pharmacology &Therapeutics, EarlyView.
New Approach Methodologies (NAMs) represent a paradigm shift in drug development and regulatory science, offering human‐relevant alternatives to traditional preclinical models. This mini‐review highlights recent advances in NAM development, validation, and regulatory application from FDA's Division of Applied Regulatory Science (DARS).
Ksenia Blinova, Kimberly Chiu, Anik Chaturbedi, Jahan Cooper, Tromondae K. Feaster, Paula L. Hyland, Lidiya Stavitskaya, Wendy W. Wu, Jeffry Florian, Rodney Rouse   +9 more
wiley   +1 more source

Editorial: Airway Surgery in Children

Frontiers in Pediatrics, 2022
Michele Torre, Rebecca Maunsell, Patricio Varela   +2 more
doaj   +1 more source

Esophageal lung, pulmonary artery sling and congenital tracheal stenosis: A case report

Journal of Pediatric Surgery Case Reports
Introduction: Esophageal lung is rare bronchopulmonary foregut malformation where a main stem bronchus is connected anomalously to the esophagus. We present a challenging diagnostic workup of a 14-month-old who was referred following multiple complicated
Norah E. Liang, Grace S. Kim, Roberto Gugig, Michael Ma, Ana Coll, Douglas Sidell, Matias Bruzoni   +6 more
doaj   +1 more source

Pressure-Controlled Volume-Guaranteed Ventilation Improves Respiratory Dynamics in Pediatric Patients During Laparoscopic Surgery: A Prospective Randomized Controlled Trial

International Journal of General Medicine, 2021
Huan Liu, Yuanyuan Cao, Lei Zhang, Xuesheng Liu, Erwei Gu Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of ChinaCorrespondence: Erwei GuDepartment of Anesthesiology, The First ...
Liu H, Cao Y, Zhang L, Liu X, Gu E
doaj  

Exploring the efficacy and safety of perampanel in epilepsia partialis continua: A case series

Epileptic Disorders, EarlyView.
Abstract Background Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus (SE), which is commonly drug‐resistant requiring treatment with multiple antiseizure medications (ASM). There are no established guidelines for pharmacological management.
Setareh Lahsaee, Kristin M. Ikeda, Stephanie Woodroffe, Benjamin P. Whatley   +3 more
wiley   +1 more source

Interdisciplinary Management of Severe Pediatric Subglottic Stenosis: A Case Report of Endoscopic Balloon Dilation Under Shared Airway Conditions

AUIQ Complementary Biological System
Pediatric acquired subglottic stenosis is a high-risk airway condition that requires close coordination between anesthesiology and otorhinolaryngology teams, particularly during endoscopic interventions performed under shared-airway conditions.
Margaretha Gunawan, Syahrial Marsintha Hutauruk, Fauziah Fardizza, Christopher Kapuangan, Mikhael Yosia   +4 more
doaj   +1 more source

Pediatric Airway Foreign Body Training Experience

MedEdPORTAL, 2013
Pediatric airway foreign body is a relatively rare but potentially life-threatening event. A significant proportion of foreign body aspirations are unwitnessed, and there are often few early symptoms after the initial coughing/gagging episode.
Garrett Griffin, Rebecca Hoesli, Marc Thorne   +2 more
doaj   +1 more source

updated review in pediatric airway management [PDF]

, 2017
With respect to anesthesia for pediatric patients, the most challenging component is airway management because it has been known to be the most significant cause of anesthesia-related morbidity or mortality. Recently, in the field of pediatric anesthesia,
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core   +1 more source