Results 81 to 90 of about 525,562 (211)

Methylphenidate and Long‐Term Risk of Cardiovascular Diseases: A Nationwide Cohort Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Cardiovascular safety of methylphenidate remains a matter of debate. Methods To evaluate the long‐term cardiovascular risk associated with methylphenidate use, a cohort study was conducted using the French National Health Data System.
Christelle Berthod   +5 more
wiley   +1 more source

The Challenges of Predicting Rare Outcomes: A Critical Appraisal of Machine Learning Using the Pediatric Resuscitation and Trauma Outcome (PRESTO) Model in a Tanzanian Injury Registry

open access: yesWorld Journal of Surgery, Volume 50, Issue 10, Page 3103-3110, October 2026.
Adding adult data did not improve predictability of the PRESTO model, possibly due to the fact that the lower mortality and injury severity in adults compared to children in our dataset statistically diluted the model. ABSTRACT Background Injuries are responsible for 950,000 deaths per year among children and adolescents under 18 years old.
Joao Vitor Perez de Souza   +9 more
wiley   +1 more source

Perforation risk in pediatric appendicitis: assessment and management

open access: yes, 2018
Erin C Howell,1 Emily D Dubina,1 Steven L Lee1,2 1Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA, USA; 2Division of Pediatric Surgery, UCLA Mattel Children’s Hospital, Los Angeles, CA, USA Abstract: Perforated appendicitis, as ...
Lee SL, Dubina ED, Howell EC
core  

Preservation Versus Routine Removal: Morbidity and Long‐Term Outcomes Following Diagnostic Laparoscopy Versus Negative Appendectomy—A Regional Multicentre Observational Cohort Study

open access: yesWorld Journal of Surgery, Volume 50, Issue 10, Page 2917-2926, October 2026.
Guidelines recommend laparoscopic appendectomy (LA) for a macroscopically normal appendix when no pathology is identified during diagnostic laparoscopy (DL) for suspected acute appendicitis (AA). This approach may lead to increased hospitalization, higher costs, and greater morbidity. Whether these guidelines are justified remains debatable.
Katrine Folmann Finne   +8 more
wiley   +1 more source

Diagnostic Value of Sodium, White Blood Cell, Neutrophil Levels; White Blood Cell/Sodium and Neutrophil/Sodium Ratios in Appendicitis in Pediatric Patients [PDF]

open access: yes
Objective: Acute appendicitis is one of the most common causes of abdominal pain requiring surgical intervention in children. Although clinical and imaging modalities play a central role in disease diagnosis, laboratory markers, such as white blood cell (
Alparslan Kapısız   +15 more
core   +1 more source

Application of the Quadratus Lumborum Block in Pediatric Gastrointestinal Surgery: A Scoping Review

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Effective pain control is critical in pediatric gastrointestinal surgery to support recovery and improve postoperative outcomes. Regional anesthetic techniques have gained increasing interest, with the quadratus lumborum block (QLB) emerging as a promising option.
Sara Marija Abu‐Bakr Christensen   +3 more
wiley   +1 more source

Diagnostic reliability of pediatric appendicitis score, ultrasound and low-dose computed tomography scan in children with suspected acute appendicitis

open access: yes, 2017
Ashraf Othman Sayed,1 Nancy Selim Zeidan,2 Dalia Monir Fahmy,3 Hossam A Ibrahim4 1Department of Pediatrics, Children and Women’s University Hospital, Minia University, El-Minya, Egypt; 2Department of Pediatrics, Faculty of Medicine, Cairo ...
Zeidan NS   +3 more
core  

Biomarker Profiling of Appendicitis in Pediatric Patients by Metabolomics, Metallomics and Inflammatory Mediator Profiling

open access: yes, 2017
Appendicitis is the most common non-traumatic surgical presentation in Pediatric Emergency Departments. The diagnosis of appendicitis is quite challenging in children due to multifactorial barriers resulting in delayed or missed diagnosis, which may ...
Shommu, Nusrat
core   +1 more source

Combining Ultrasound with a Pediatric Appendicitis Score to Distinguish Complicated from Uncomplicated Appendicitis in a Pediatric Population

open access: yesActa Informatica Medica, 2020
The accurate diagnosis of complicated appendicitis has been improved by using various diagnostic modalities. However, no preoperative diagnostic method could completely confirm the results. Therefore, preoperative diagnosis of complicated appendicitis to have the right management is still a huge challenge.The aim of this study was to evaluate the ...
Hao, Tran Kiem   +4 more
openaire   +3 more sources

Change of substance‐related hospitalisation in adolescents after cannabis legalisation in Thailand in 2022

open access: yesAddiction, Volume 121, Issue 10, Page 2768-2779, October 2026.
Abstract Background and aims On 9 June 2022, Thailand changed its cannabis legislation, expanding access to individuals aged >18 years. Evidence suggests that such changes could increase the risk of cannabis use and related harms, and could influence patterns of use of other substances among adolescents.
Sirada Puetpaiboon   +7 more
wiley   +1 more source

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