Results 41 to 50 of about 492 (130)

Diagnostic Accuracy of Inflammatory Biomarkers in Differentiating Acute Appendicitis From Other Acute Abdomen and Predicting Disease Severity: A Prospective Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Acute appendicitis (AA) is one of the most common clinical conditions for emergency surgery. The diagnosis of acute appendicitis remains challenging for surgeons. Researchers are still looking for a parameter that is less expensive and easily available for diagnosis.
Sintayehu Admas, Bisrat Birke Teketelew, Nigusie Alemu, Berhanu Woldu, Lyusira Marelgn, Getu Girmay, Arega Zenaw, Abebe Birhanu, Yemataw Gelaw   +8 more
wiley   +1 more source

Retrospective Multivariate Analysis of Data from Children with Suspected Appendicitis: A New Tool for Diagnosis

Emergency Medicine International, 2018
Background. Decision-making for management may sometimes be difficult in acute appendicitis (AA). Various diagnostic scoring systems exist, but their sensitivity and specificity rates are far from ideal. In this study, the determination of the predictors
Zafer Dokumcu, Bade Toker Kurtmen, Emre Divarci, Petek Bayindir Tamay, Timur Kose, Murat Sezak, Geylani Ozok, Orkan Ergun, Ahmet Celik   +8 more
doaj   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Large Language Models for Explainable Medical Text Summarization: A Systematic Literature Review

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 2, June 2026.
The graphical abstract highlights the three key aspects addressed in this review: the technical background of medical text summarization methods relevant to clinical decision support; the LLM background in providing context for its diagnosis and clinical significance; and clinical decision support with summarization and explainability in patient care ...
Aleka Melese Ayalew, Md Rabiul Hasan, Tapio Seppänen, Mourad Oussalah   +3 more
wiley   +1 more source

Artificial Intelligence in Type 1 Diabetes Management: A Scoping Review of Randomised Controlled Trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4860-4875, June 2026.
ABSTRACT Background Artificial intelligence is emerging in healthcare systems. In type 1 diabetes, AI‐enabled tools are increasingly used to support nutrition assessment and insulin decision‐making, yet their clinical utility and safety remain unclear. Methods The study aims to identify and map the evidence on the clinical utility of AI‐based diabetes ...
Yucen Wu, Jun Pang, Shaoyong Xu, Lalantha Leelarathna, Aaron M. Lett   +4 more
wiley   +1 more source

Bowel Ischemia: A Life‐Threatening Complication of an Infected Urachal Cyst in an Adolescent

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT While infection is a recognized complication of congenital urachal cysts, progression to an inflammatory phlegmon causing bowel ischemia is an exceptionally rare and life‐threatening event in the pediatric population. We report the case of a 14‐year‐old male with a 7‐year history of an infraumbilical mass who presented with an acute abdomen ...
Sheeraz Ali, FNU Saliha, Bilal Ahmad, Abdul Eizad Asif, Khalil El Abdi, Bilal Aslam, Fazeela Bibi, Said Hamid Sadat   +7 more
wiley   +1 more source

Evaluating the Potential Infectious Risk Profile of Biologics in Chronic Rhinosinusitis With Nasal Polyposis

International Forum of Allergy &Rhinology, Volume 16, Issue 7, Page 751-754, July 2026.
Maxime Fieux, Philippe Gevaert, Leigh J. Sowerby   +2 more
wiley   +1 more source

Clinical Features, CT Imaging Decisions and Yield by Age in Adults With Abdominal Pain in the Emergency Department

Academic Emergency Medicine, Volume 33, Issue 5, May 2026.
ABSTRACT Objectives Older adults with abdominal pain present diagnostic uncertainty due to less informative histories/exams, broader etiologies, and higher morbidity. Whether ED imaging decisions are calibrated to this risk is unclear. The objective of this study was to compare age‐stratified clinical features, CT utilization, and CT diagnostic yield ...
Ari B. Friedman, Michael N. Adjei‐Poku, Liliana A. Schadt, Yang Li, Anne R. Cappola, Rachel R. Kelz, Ula Hwang, Gopal Kowdley, Aubrey Mwinyogle, N. Seth Trueger   +9 more
wiley   +1 more source

Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 841-855, May 2026.
This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin, Marie Tauber, Robert Sidbury, Jonathan I. Silverberg, Kim A. Papp, Diamant Thaçi, Marjolein S. De Bruin‐Weller, Adam Reich, Ketty Peris, Kirk Barber, Ryszard Galus, Andrzej Kaszuba, Matthew Zirwas, Walter K. Nahm, Gretel Trullenque, Laura Maintz, Sady Alpizar, Sang Wook Son, Vivian Laquer, Linda Stein Gold, Soo Yeon Cheong, Anna Ryzhkova, Agnes Drahos, Liliana Ulianov, Christophe Piketty   +24 more
wiley   +1 more source

Repensando el Pediatric Appendicitis Score: limitaciones de su aplicabilidad diagnóstica en cirugía pediátrica

Revista Colombiana de Cirugía
Hemos leído con particular interés el estudio de Barón-Méndez LE, et al. 1 titulado: “Utilidad del Pediatric Appendicitis Score (PAS) para el diagnóstico de apendicitis aguda en pacientes pediátricos”, que tuvo por objetivo determinar el rendimiento del
Jorge Andrés Castrillón-Lozano, Juan Andrés Lozano-Arce, Ricardo Leonel Arroyave-Zuluaga   +2 more
doaj   +1 more source