Results 301 to 310 of about 99,855 (366)
Abstract This study aims to systematically review evidence on gut microbiota‐based interventions for reducing depression‐ and anxiety‐like symptoms in children and adolescents with autism spectrum disorder, irritable bowel syndrome, Prader‐Willi syndrome, below‐average literacy skills or anorexia nervosa, where some individuals may exhibit indicators ...
Jiayu Hu+4 more
wiley +1 more source
Abstract Objectives Biliary strictures (BS) remain frequent after pediatric liver transplantation (pLT) and best management practices are still lacking. This study systematically assesses efficacy of stricture treatment by percutaneous transhepatic cholangiography and drainage (PTCD). Methods Online databases were searched for studies on PTCD treatment
Jonathan Seisenbacher+6 more
wiley +1 more source
Abstract Constitutional mismatch repair deficiency (CMMRD) is a rare hereditary cancer syndrome resulting from biallelic mutations in DNA mismatch repair (MMR) genes that lead to early‐onset cancers in children, including lymphoma and colorectal cancer (CRC).
Chloe J. Cohan+3 more
wiley +1 more source
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Ashley Polachek+6 more
wiley +1 more source
Upadacitinib for difficult‐to‐treat paediatric Crohn's disease
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou+3 more
wiley +1 more source
Genital Crohn's disease in pediatrics and genetic associations
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang+5 more
wiley +1 more source