Results 51 to 60 of about 7,386 (125)
Internet Health Resources [PDF]
, 2003 Presents findings from a survey conducted in December 2002.
Deborah Fallows, Susannah Fox
core
Potential Roles of Adropin in Central Nervous System: Review of Current Literature [PDF]
, 2016 Adropin is a 4.9 kDa peptide that is important for maintenance of metabolic and non-metabolic homeostasis. It regulates glucose and fatty acid metabolism and is involved in endothelial cell function and endothelial nitric oxide (NO) synthase bioactivity ...
Ramin Zand +3 more
core +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding. [PDF]
, 2016 Fragile X premutation alleles have 55-200 CGG repeats in the 5' UTR of the FMR1 gene. Altered zinc (Zn) homeostasis has been reported in fibroblasts from >60 years old premutation carriers, in which Zn supplementation significantly restored Zn ...
Gane, Louise W +8 more
core +3 more sources
Genetic Risk Factors for Poor Cognitive Outcome Following Brain Insult—A Systematic Review
Brain and Behavior, Volume 16, Issue 1, January 2026.This systematic review summarizes genetic predictors of cognitive outcomes following stroke, traumatic brain injury, and other brain insults. APOE‐ε4 consistently predicts poorer cognitive recovery. Evidence for the COMT rs4680 G allele suggests adverse associations, while BDNF findings remain inconsistent.
Tora Dunås +8 more
wiley +1 more source
Cognitive-behaviour therapy and skilled motor performance in adults with chronic tic disorder [PDF]
, 2015 The first aim of the present study was to compare performance of people with tic disorders (TD) and controls on executive function and a range of skilled motor tests requiring complex performance, guided movements, hand co-ordination, and fine control of
Borgeat, F. +4 more
core +1 more source
MedComm, Volume 7, Issue 1, January 2026.The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li +5 more
wiley +1 more source
Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions
MedComm, Volume 7, Issue 1, January 2026.The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin +3 more
wiley +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Genetic Discrimination: Overview of the Issue and Proposed Legislation [PDF]
, 2007 [Excerpt] A key policy issue before Congress is whether the potential for genetic discrimination by employers and insurers merits protections for genetic information that are more extensive than those already in place for health information.
Redhead, C. Stephen +2 more
core +1 more source