Results 141 to 150 of about 153,965 (262)

Core temperature measurement methods and their accuracy in pediatric intensive care units: a narrative review. [PDF]

Front Pediatr
Chen H, Huang H, Ning J, Li Y, Qiao L.
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Changes in Academic Standardized Testing After Pediatric Intensive Care.

JAMA Netw Open
Foster CC, Boyd M, Carlton EF, Fussell J, Slaton CR, McKenzie S, Irby K, Mourani PM, Brown CC, Maddux AB.   +9 more
europepmc   +1 more source

Evaluation of visitation policies and family information practices in pediatric intensive care units in Turkey: a national survey. [PDF]

Eur J Pediatr
Emeksiz S, Bayramov B, Oglakcioglu A, Ozcan S, Kendirli T.   +4 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Navigating Culture and Crisis: Saudi Mothers' Experiences of Family-Centered Care in Pediatric Intensive Care Units-A Qualitative Study. [PDF]

Healthcare (Basel)
Alshehri WM, Almutairi A, Eid T, Almutairi AS, Almutairi RR, Almutairy BM, Alshaibany FF, Almutairi WA, Almutairi AA, Alodhailah AM.   +9 more
europepmc   +1 more source

Pediatric Intensive Care [PDF]

Archives of Disease in Childhood, 1989
openaire   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Clinical and Epidemiological Characteristics of Ventilator-associated Pneumonia in Pediatric Intensive Care Units. [PDF]

Adv Biomed Res
Babai S, Parastegari M, Zibanejad N.
europepmc   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source