Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
Change in Nutritional Status of Children in the Pediatric Intensive Care Unit over First 14 Days: A Prospective Cohort Study. [PDF]
Loyi M, Mishra D, Jhamb U, Saxena R.
europepmc +1 more source
Abstract The human mandibular symphysis concentrates multiaxial loads during function and remodels throughout growth, but the precise mechanisms underlying cortical bone shape during growth remain relatively unexplored. Approaches based solely on thickness or external cortical contours provide only partial insights and do not capture the functional ...
Ana Ribeiro +3 more
wiley +1 more source
Changes in Academic Standardized Testing After Pediatric Intensive Care.
Foster CC +9 more
europepmc +1 more source
Association between admission undernutrition and mortality rates and adverse outcomes in a pediatric intensive care unit in India: a prospective cohort study. [PDF]
Kalrao VR, Pramod A.
europepmc +1 more source
Purpose To compare postoperative complications, rehabilitation outcomes, and health care utilization in children undergoing primary medial patellofemoral ligament reconstruction for patellofemoral instability with and without a pre‐existing mental illness. Methods The TriNetX U.S.
Haad A. Arif +4 more
wiley +1 more source
Breastfeeding support in Italian Pediatric Intensive Care Units: a nationwide survey on protocols, practices, and challenges. [PDF]
Morniroli D +8 more
europepmc +1 more source
Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further
Greta Rogani +17 more
wiley +1 more source
Delirium and Iatrogenic Withdrawal Profiles in the Pediatric Intensive Care Unit (PICU): A Latent Profile Analysis of Nurse-Administered Bedside Scales. [PDF]
Matsuishi Y +8 more
europepmc +1 more source
Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret +2 more
wiley +1 more source

