Results 191 to 200 of about 329,701 (306)

Longitudinal Phenotypic Trajectories in GNAO1‐Related Disorders: Defining Disease Progression and Clinical Profiles

Annals of Neurology, EarlyView.
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral, Ana María Domínguez Cobo, Sol Balsells, Anna Aguilar‐Ros, Chu‐Ting Chang, William G. Ludlam, Kathryn Yang, Katerina Bernardi, Micaela Chinigioli, Ainara Salazar‐Villacorta, Veronica Di Pisa, Nuria Lamagrande‐Casanova, Elena González‐Alguacil, Beatriz De la Casa‐Fages, Akihisa Okumura, Josefina Rodríguez, Ayush Agarwal, Daniela Muñoz‐Chesta, Carolina Reynoso‐Osnayo, Amy Lin, Brahim Tabarki, Jobaida Parvin, Adolfo Alberto Gallo, Andreia Forno, Fabian Maass, Johnny Montiel Blanco, Salomé Nasif, Elizabeth Jennions, Jorge Luis Ramón‐Gómez, Helene Verhelst, Juan José Nieto Barceló, Dunja Čokolić Petrović, Luz Victoria García Ruiz, Christoph van Riesen, Paulo Rego Sousa, Maria del Pilar Massaro Sanchez, Husnea Ara Khan, Wejdan Hakami, Jennifer Friedman, Iván Espinoza‐Quinteros, Monica Troncoso, Divyani Garg, Micaela Pauni, Hirokazu Kurahashi, María Concepción Miranda‐Herrero, Anna Duat‐Rodriguez, Luca Soliani, Manju A. Kurian, Angeles Schteinschnaider, Siddharth Srivastava, Darius Ebrahimi‐Fakhari, Kirill A. Martemyanov, Juan Darío Ortigoza‐Escobar   +52 more
wiley   +1 more source

Effectiveness of combined versus single circadian interventions in neonatal and pediatric intensive care units: a systematic review with meta-analysis. [PDF]

Front Neurol
Corrotea-Maltez CC, Fernández-Flores CV, Gutiérrez-Neira CL, Nirrian-Pérez AJ, Mansilla-Muñoz J, Bustos-González L.   +5 more
europepmc   +1 more source

Cortical bone distribution in the human mandibular symphysis: Ontogenic and morphometric approaches in archeological context

The Anatomical Record, EarlyView.
Abstract The human mandibular symphysis concentrates multiaxial loads during function and remodels throughout growth, but the precise mechanisms underlying cortical bone shape during growth remain relatively unexplored. Approaches based solely on thickness or external cortical contours provide only partial insights and do not capture the functional ...
Ana Ribeiro, Elsa Garot, Christine Couture, Pierre‐Hadrien Decaup   +3 more
wiley   +1 more source

Over‐the‐Top Anterior Cruciate Ligament Reconstruction With Lateral Extra‐articular Tenodesis in Pediatric Athletes Provides Excellent Functional Outcomes and Preserves Growth Plate Symmetry

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess clinical and radiological outcomes of pediatric anterior cruciate ligament (ACL) reconstruction using the over‐the‐top technique (OTT) combined with the lateral extra‐articular tenodesis (LET) technique in skeletally immature patients, providing insights into its safety, efficacy, and effects on the growing knee.
Abel Gomez‐Caceres, Ivan Medina‐Porqueres, Manuel Benavides Propp, Almudena Perez Lara, Ignacio Vieitez‐Riestra, Raphael Pierre Idiart‐Charrier, Iskandar Tamimi‐Mariño   +6 more
wiley   +1 more source

Understanding infant stress in neonatal and pediatric intensive care: a scoping review. [PDF]

Intensive Care Med Paediatr Neonatal
Riley C, Mastropietro C, Darcy-Mahoney A, Pintz C, Zhou QP, Hinds PS.   +5 more
europepmc   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Teamwork and job satisfaction among nurses in pediatric intensive care unit. [PDF]

Sci Rep
Fahimeh S, Niusha R, Monireh FG, Mahbobeh A.   +3 more
europepmc   +1 more source

Surgical Management of Anterior Cruciate Ligament Rupture in Skeletally Immature Adolescents: A Bilateral Transphyseal All‐Inside Technique With Patient‐Specific Bone Tunnels and Semitendinosus Autograft

Arthroscopy Techniques, EarlyView.
Abstract In recent years, with the widespread participation in athletic activities, the incidence of anterior cruciate ligament (ACL) ruptures among adolescent populations has shown an increasing trend. Without timely intervention, this condition can lead to meniscal tears, accelerated articular cartilage wear, and early‐onset osteoarthritis, severely ...
Zeming Li, Junling Luo, Chuanliang Chen, Shifeng Zhong, Hao Feng, Hongtao Wang, Jun Yao   +6 more
wiley   +1 more source

Evaluation of Pediatric Cardiomyopathy Patients in Pediatric Intensive Care Unit. [PDF]

Turk Arch Pediatr
Kesen Ş, Havan M, Ramoğlu M, Uçar T, Tutar E, Kendirli T.   +5 more
europepmc   +1 more source