Results 121 to 130 of about 5,932,451 (312)

Clinical Characteristics and Outcomes of Pediatric Oncology Patients Admitted to the Pediatric Intensive Care Unit: A Single Center Experience in Saudi Arabia

Background/Objectives: Advances in pediatric oncology have improved survival; however, critically ill children with cancer remain at high risk for adverse outcomes and frequently require admission to the pediatric intensive care unit (PICU).
Aljizani, Wafaa, Othman, Fatmah, Faisal Althaqeel, Wafaa Aljizani, Fatmah Othman, Obaid Alfuraydi, Alrashed, Faisal, Faisal Alrashed, Althaqeel, Faisal, Alfuraydi, Obaid   +9 more
core   +1 more source

Assessment of Healthcare-Associated Infections in Pediatric Intensive Care Unit

, 2021
Objective: In this study, it was aimed to determine the incidence and rate of healthcare-associated infections, and to determine the susceptible microorganisms and antibiotic susceptibilities by examining the patients hospitalized in our Pediatric ...
Ciftdemir, Nukhet Aladag, Duran, Ridvan, Cataltas, Elif Damla Oz   +2 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Metagenomic next-generation sequencing to detect Pneumocystis jirovecii pneumonia in critically ill, HIV-negative children: a retrospective multicenter study

BMC Pulmonary Medicine
Background Metagenomic next-generation sequencing (mNGS) plays a critical role in the rapid detection of infectious pathogens. We aimed to analyze the clinical characteristics of Pneumocystis jirovecii infection in children without HIV infection and to ...
Liming He, Yibing Cheng, Li Huang, Zhenyu Zhang, Qunqun Zhang, Ling Gong, Tian Li, Xiulan Lu, Xiaodi Cai, Gangfeng Yan   +9 more
doaj   +1 more source

Pediatric palliative care in the intensive care unit and questions of quality: a review of the determinants and mechanisms of high-quality palliative care in the pediatric intensive care unit (PICU).

Translational Pediatrics, 2018
This article reviews the state and practice of pediatric palliative care (PC) within the pediatric intensive care unit (PICU) with specific consideration of quality issues. This includes defining PC and end of life (EOL) care. We will also describe PC as
S. R. Short, R. Thienprayoon
semanticscholar   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Is routine preoperative head ultrasound screening before congenital cardiac surgery mandatory?

The Cardiothoracic Surgeon
Background The practice of routine preoperative head ultrasound (HUS) screening for infants and neonates undergoing surgery for congenital heart disease has been widely adopted; however, its usefulness is still unclear.
Shawana Farooq, Hanan Rashid Abu Hassan, Omai Mohammed AlSassi, Tarek Alfawzan, Abdullah Eltayeb, Seifeldin Mohamed, Suffura Rafique, Ghaida Mohammed Ali, Tarek Jamal Alanezi, Ali Hussain Alharbi, Brahim Tabarki, Abdullah Al Wadai   +11 more
doaj   +1 more source

Evaluation of Central Venous Catheterization Complications and Related Risk Factors in a Pediatric Intensive Care Unit

, 2016
Objective: In this study, we aimed to evaluate central venous catheter insertion related complications and related risk factors in a pediatric intensive care ...
Coskun, Ramazan, Ozcan, Alper, Kose, Secil, Torun, Yasemin Altuner, Ergul, Ayse Betul, Aslaner, Haci Ahmet, Aslaner, Humeyra   +6 more
core   +1 more source

Adams-Oliver syndrome, a successful conservative approach for a large scalp defect

Journal of Pediatric and Neonatal Individualized Medicine, 2015
Adams-Oliver syndrome was first described in 1945 as a multiple congenital malformations association including aplasia cutis congenita and terminal transverse limb defects, along with cardiovascular and central nervous system anomalies.
Vera Baptista, Albina Silva, Carla Sá, Joana Dias, Ana Raquel Silva, Angélica Osório, Carla Garcez, Almerinda Pereira   +7 more
doaj   +1 more source