Results 71 to 80 of about 5,778,311 (262)

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Early mobilization in the pediatric intensive care unit [PDF]

Translational Pediatrics, 2018
Survivors of critical illness often experience multiple morbidities that start in the intensive care unit and impact their quality of life after discharge. Reduced physical function, cognitive decline, feeding disorders, and psychological stress are just a few of the potential complications.
Tracie C, Walker, Sapna R, Kudchadkar
openaire   +2 more sources

Retrospective Analysis of Cases with Guillain-Barré Syndrome in Pediatric Intensive Care Unit

, 2017
Introduction: The aim of this study was to evaluate treatment approaches towards Guillain-Barré syndrome and treatment response in patients with Guillain-Barré syndrome admitted to the pediatric intensive care unit. Methods: We retrospectively evaluated
Nermin Ankay, Esra Şevketoğlu, Osman Yeşilbaş, Mey Talip Petmezci, Hasan Serdar Kıhtır, Zeynep Kıhtır   +5 more
core   +1 more source

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]

, 2014
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
Vitón-Castillo, Adrián Alejandro, Mebazaa, A, Mebazaa, A. (Alexandre), Antonelli, M, Rhodes, A. (Andrew), Backer, D. (Daniel) de, Pinsky, MR, Teboul, JL, Bakker, J. (Jan), Vincent, JL, Pinsky, Michaël, Christoph Hofer, Jean Louis Vincent, Teboul, J.L. (Jean Louis), Beale, R, Daniel De Backer, Jaeschke, R, Rhodes, A, Jaeschke, Roman, Hofer, C, Jaeschke, R. (Roman), Teboul, Jean Louis, Mebazaa, Alexandre, Cecconi, M. (Maurizio), De Backer, Daniel, Antonelli, Massimo, Massimo Antonelli, Antonelli, M. (Massimo), Viruez-Soto, José Antonio, Bakker, Jan, Hofer, C. (Christoph), Auza-Santivañez, Jhossmar Cristians, Maurizio Cecconi, Vincent, J.-L. (Jean-Louis), Jean Louis Teboul, Roman Jaeschke, Beale, R. (Richard), Vincent, Jean Louis, Hofer, Christoph, Pinsky, M.R. (Michael), Michael R. Pinsky, Bakker, J, Richard Beale, Rhodes, Andrew, Alexandre Mebazaa, Luperón Loforte, Daysi, Cecconi, M, De Backer, D, Jan Bakker, Beale, Richard, Bakker, Jan; id_orcid, Cecconi, Maurizio, Andrew Rhodes   +52 more
core   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Evaluation of Patients Receiving High-flow Nasal Cannula Oxygenation Therapy in a Pediatric Intensive Care Unit

, 2022
Objective:Patients hospitalized in pediatric intensive care units require various rates of respiratory and oxygen support therapies. Invasive and non-invasive treatment methods are used as respiratory support treatment, and new technologies are being ...
İlknur Arslan Tolunay, Orkun Tolunay, Gülümay Vural   +2 more
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Determining the Difficulties of Parents with Children in Home Care Who Were Discharged from Intensive Care [PDF]

Introduction: This study was performed to determine the difficulties experienced by parents with children in home care who were discharged from intensive care.
Gülzade Uysal, Atiye Karakul, Duygu Sönmez Düzkaya, Gülçin Bozkurt, Tülay Yakut   +4 more
core   +1 more source

Development and evaluation of the focused assessment of sonographic pathologies in the intensive care unit (FASP-ICU) protocol

, 2023
Background The use of ultrasonography in the intensive care unit (ICU) is steadily increasing but is usually restricted to examinations of single organs or organ systems.
Quintel, Michael, Schmidt, Stefan, Dieks, Jana-Katharina, Moerer, Onnen, Schmidt, Stefan; Department of Anesthesiology, Emergency and Intensive Care Medicine, University Hospital Goettingen, Georg August University, Goettingen, Germany, Quintel, Michael; Department of Anesthesiology, Emergency and Intensive Care Medicine, University Hospital Goettingen, Georg August University, Goettingen, Germany, Moerer, Onnen; Department of Anesthesiology, Emergency and Intensive Care Medicine, University Hospital Goettingen, Georg August University, Goettingen, Germany, Dieks, Jana-Katharina; Department of Pediatric Cardiology and Pediatric Intensive Care Medicine, University Hospital Goettingen, Georg August University, Goettingen, Germany   +7 more
core   +1 more source