Results 81 to 90 of about 251,583 (301)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

The most frequent nursing diagnosis in pediatric intensive care unit

Revista de Enfermagem da Universidade Federal de Santa Maria, 2015
Aim: to identify the ten most frequent nursing diagnosis in hospitalized patients in a Pediatric Intensive Care Unit. Method: cross-sectional study with 30 patients in a Pediatric Intensive Care Unit.
Danila Maria Batista Guedes, Lisabelle Mariano Rossato, Eloíde André Oliveira   +2 more
doaj   +1 more source

The Role of Alaska's Nurse Practitioners in Preventing Early Childhood Caries [PDF]

, 2014
Early Childhood Caries (ECC) is the most common chronic disease of childhood despite being preventable. Because of its high prevalence, its impact on the quality of life of young children, and its potential for increasing their risk of caries in the ...
Maixner, Margaret
core  

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Pediatric Kennedy Terminal Ulcer [PDF]

, 1999
Photograph of Fossett's circus loads, 2 AEC Matadors - KKN412 - and trailers, taken Forest site, 28 September 1959 whole side ...
Reitz, Megan, Schindler, Christine A.
core   +2 more sources

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

A Review of Literature on Health-Related Quality of Life of Retinoblastoma Survivors. [PDF]

, 2020
Background: Retinoblastoma is a malignant tumor of the eye that typically presents in early childhood and occurs in approximately 1 in 20,000 births. While active treatment of the tumor is typically completed in childhood, survivors often suffer from ...
Belson, Paula J, Brecht, Mary-Lynn, Eastwood, Jo-Ann, Hays, Ron D, Pike, Nancy A   +4 more
core  

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Balancing Consent, Confidentiality, and Child Welfare: A Narrative Review of Ethical Dilemmas in Pediatric Nursing [PDF]

Journal of Client-centered Nursing Care
Background: Pediatric nursing faces a range of ethical challenges that are markedly different from those encountered in adult care, particularly concerning informed consent, confidentiality, and the welfare of children.
Maryam Modabber, Marzieh Maleki, Elham Salahi   +2 more
doaj