Results 231 to 240 of about 205,410 (305)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Evaluating the Effectiveness of the Motivational Interviewing-Based Wellness Coaching for Kids and Families (WC4K) Program in Pediatric Obesity Care: Protocol for a Cluster Randomized Pragmatic Trial.

JMIR Res Protoc
Koebnick C, Sidell M, Vallejo JD, Li X, Delacroix E, Young D, Kunani P, Resnicow K.   +7 more
europepmc   +1 more source

Racial and ethnic disparities in clinical trials for pediatric obesity. [PDF]

Obesity (Silver Spring)
Coughlin CG, Zoltick ES, Stanford FC, Ong MS.   +3 more
europepmc   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Plasma amino acid profiles in pediatric obesity: potential biomarkers for the early assessment of metabolic risk. [PDF]

Front Pediatr
Öge Enver E, Duygu A, Vatansever P, Yılmaz B, Akın Y.   +4 more
europepmc   +1 more source

Chinese Expert Consensus on the Use of Ultrasound‐Derived Fat Fraction in the Assessment of Metabolic Dysfunction‐Associated Steatotic Liver Disease (2025 Edition)

Portal Hypertension &Cirrhosis, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become one of the leading causes of chronic liver diseases in China and even globally. Early non‐invasive diagnosis and grading MASLD, along with timely intervention, are crucial for assessing the disease condition and slowing the disease progression.
Liyun Xue, Yuli Zhu, Huixiong Xu, Hong Ding   +3 more
wiley   +1 more source

Ability of triglyceride-glucose indices to predict metabolic dysfunction associated with steatotic liver disease in pediatric obesity. [PDF]

J Pediatr Gastroenterol Nutr
Di Bonito P, Di Sessa A, Licenziati MR, Corica D, Wasniewska MG, Morandi A, Maffeis C, Faienza MF, Mozzillo E, Calcaterra V, Franco F, Maltoni G, Miraglia Del Giudice E, Umano GR, Valerio G.   +14 more
europepmc   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

A Systemic Review of Pharmacological Management of Pediatric Obesity. [PDF]

J Pharm Bioallied Sci
Gupta S.
europepmc   +1 more source