Results 241 to 250 of about 211,807 (284)

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo   +10 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Dosing Biologic Drugs for Patients With Obesity: One Size Does Not Fit All

open access: yes
Arthritis &Rheumatology, EarlyView.
Stephen J. Balevic   +2 more
wiley   +1 more source

Pediatric Glial Tumors

Pediatric and Developmental Pathology, 2021
Pediatric glial tumors are unique from their adult counterparts. This important distinction is recognized and incorporated into the World Health Organization classification of central nervous system tumors and applies to both high- and low-grade gliomas, incorporating their specific molecular profiles.
Angela N, Viaene   +2 more
openaire   +2 more sources

Pediatric Brain Tumors

Continuum, 2017
This article describes the most common pediatric brain tumors and highlights recent developments in their diagnosis and treatment strategies.We are in the midst of a molecular era for pediatric brain tumors. Genetic and epigenetic profiling of tumors has impacted their diagnosis, allowing for the subgrouping of heterogeneous tumor groups and leading to
Mai, Dang, Peter C, Phillips
openaire   +4 more sources

Pediatric Brain Tumors

Continuum, 2020
This article focuses on primary brain tumors in the pediatric population with an emphasis on molecular classifications and treatment strategies.Pediatric brain tumors are a heterogeneous group of tumors that differ from adult brain cancers despite similar nomenclature.
Sonia, Partap, Michelle, Monje
openaire   +2 more sources

Pediatric Pituitary Tumors

Neurosurgery, 1991
Abstract This retrospective review of pediatric patients with pituitary tumors causing onset of symptoms by 17 years of age was done to define their pathological distribution, clinical presentation, treatment, and prognosis. Eighteen patients were evaluated and treated from 1979 to 1989.
S F, Haddad   +2 more
openaire   +2 more sources

Pediatric genitourinary tumors

Current Opinion in Oncology, 1999
Advances in our knowledge of pediatric genitourinary tumors are being made at a rapid pace at both the basic science and clinical levels. As the molecular mechanisms underlying these malignancies are being uncovered, treatment options are being modified to decrease morbidity and, ultimately, increase survival. This article reviews the recent literature
H H, Lee   +4 more
openaire   +2 more sources

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