Results 231 to 240 of about 1,251,614 (342)

Pediatric Dacryocystorhinostomy

Indian Journal of Ophthalmology, 2017
openaire   +3 more sources

Epigenetic Targeting of Senescent Cells Prevents the Deleterious Effects of Obstructive Sleep Apnea on Growing Skeleton

Advanced Science, EarlyView.
Chronic intermittent hypoxia induces premature senescence of osteoprogenitor cells in long bone metaphysis via HIF1α‐mediated EZH2‐H3k27me3 downregulation, leading to impaired bone growth. Restoration of H3K27me3 level via UTX inhibition rescues osteogenesis and growth impairment in young mice.
Xiaonan Liu, Peilin Zhang, Zhongyi Su, Yong Feng, Zhenger Zhou, Sa Pang, Yicheng Wang, Jiacheng Hu   +7 more
wiley   +1 more source

Understanding the Cognitive Load of Cross-Cover Care: The Resident's Perspective. [PDF]

J Grad Med Educ
McDermott C, McNeely M, Vinson A, Hartley S, Hughes DT, Heidemann LA.   +5 more
europepmc   +1 more source

Impact of implementing a structured patient handoff oncommunication in a pediatrics residency program

O.-E. Lund, Facundo Jorro Barón, Cristian García Roig   +2 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Distal Catheter Migration into Scrotum as a Rare Complication of Ventriculoperitoneal Shunt in Pediatrics; A Case Series

, 2019
Ali Abdoli, Manouchehr Ghorbanpour, Afshin Fayyazi, Mohammad Reza Saatian   +3 more
openalex   +2 more sources

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

Correction to Patient Page.

JAMA Pediatr
europepmc   +1 more source

Achievable Benchmarks of Care in Low-Value Care Delivery in Children's Hospitals. [PDF]

Pediatrics
Shine A, Hall M, De Souza HG, Harrison W, Coon ER, Schroeder AR, Reyes M, Ralston SL, House SA.   +8 more
europepmc   +1 more source