Results 31 to 40 of about 775,235 (307)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Вопросы современной педиатрии, 2020 Psoriasis is one of the most debatable topics in modern dermatology among the wide range of other dermatological diseases in childhood. The article provides current data on the epidemiology of psoriasis, its clinical features in different age groups, its
Andrey L. Bakulev +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Aktualʹnaâ Infektologiâ, 2016 The paper deals with the problems of diagnosis, differentiated diagnosis, dispensary for disease, prevention and treatment of poliomyelitis in children. There are presented the WHO guidelines on poliomyelitis for Ukraine.
O.K. Koloskova +2 more
doaj +1 more source
Directed Acyclic Graphs: a Tool for Causal Studies in Pediatrics
Pediatric Research, 2018 Many paediatric clinical research studies, whether observational or interventional, have as an eventual aim the identification or quantification of causal relationships. One might ask: does screen time influence childhood obesity?
T. Williams +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Вопросы современной педиатрии, 2016 Objective: Our aim was to clarify and standardize the definitions of the term "social pediatrics."Methods: Terminological analysis, functional interpretative content analysis and method of expert assessments.Results: We found 86 definitions of the term ...
Natalia V. Ustinova
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Sakarya Tıp Dergisi, 2012 IntroductionThe aim of this study is to compare the level of knowledge about Pediatrics Cardio Pulmonary Resuscitation (CPR) between pediatrics and emergency residents.MethodIn this cross-sectional study, the standard questionnaire about pediatrics ...
Mostafa Vafaei Aghdam +4 more
doaj +1 more source
A Review of Neurostimulation for Epilepsy in Pediatrics
Brain Science, 2019 Neurostimulation for epilepsy refers to the application of electricity to affect the central nervous system, with the goal of reducing seizure frequency and severity.
K. Starnes +3 more
semanticscholar +1 more source