Results 251 to 260 of about 224,320 (332)
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef+12 more
wiley +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen+10 more
wiley +1 more source
Identification of candidate genes associated with bipolar disorder by whole-exome sequencing of a Chinese multi-affected pedigree. [PDF]
Wang Y, Xu Z, Zhang Y, Li H.
europepmc +1 more source
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang+14 more
wiley +1 more source
Assessment of genetic diversity and inbreeding in the Okinawa indigenous Agu pig through pedigree analysis. [PDF]
Touma S, Fusho K, Arakawa A.
europepmc +1 more source
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Reproductive Results of Selected Cat Breeds. [PDF]
Wójcik W, Piechowska M.
europepmc +1 more source