Results 71 to 80 of about 9,370 (218)

Mothers of Future Kings: The Madonna Redux Phenomenon [PDF]

open access: yes, 2013
The visual culture that created Diana was motivated by Victorian constrictions of motherhood that enforced notions of stability and lineage. This article examines the cultural metaphors of nurturance – the “Madonna redux phenomenon” – in images of Diana,
Denney, Colleen
core   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

open access: yesAdvanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou   +22 more
wiley   +1 more source

Rebellious uniform [PDF]

open access: yes, 2012
In this thesis, I focus on adolescent teens at Kingswood College High School, where I am currently employed as a student assistant in Grahamstown. I form part of a networked hierarchy at Kingswood College whereby I am expected to perform duties which ...
Farmer, Mark Ross
core   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

Investigation of the GATA repetitive DNA sequence of the domestic horse (Equus caballus) of: a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University [PDF]

open access: yes, 1990
The variation in copy number and organisation of the simple quadruplet repeat (GATA)n in the genome of most animals has made it a .potential tool for DNA fingerprinting.
Ede, Andrea J
core  

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

open access: yesAdvanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen   +14 more
wiley   +1 more source

A Hall For Hercules At Ostia And A Farewell To The Late Antique >Pagan Revival> [PDF]

open access: yes, 2010
In 1945, Herbert Bloch published an inscription from Ostia recording the restoration of a cellam Herc[ulis] in the late fourth century and suggested that it heralded the last pagan revival in the western Roman empire.
Boin, Douglas R.
core  

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

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