Results 71 to 80 of about 181,308 (201)

Investment Returns and Risk for Art: Evidence from Auctions of American Paintings [PDF]

open access: yes
The literature on return and risk for investment in paintings is extended by disaggregating for artist, genre, and quality. A hedonic log price model generates yearly price indices and shadow values for painting characteristics using a large sample of U ...
Richard J. Agnello
core  

Pedigree-based (FPED), ROH-based (FROH) and microsatellite-based (FMIC) inbreeding coefficients for highly inbred (HI) and outbred (LI) bulls.

open access: yes, 2018
Pedigree-based (FPED), ROH-based (FROH) and microsatellite-based (FMIC) inbreeding coefficients for highly inbred (HI) and outbred (LI) bulls.
Hao Cheng (103394)   +7 more
core   +1 more source

Ancient DNA from a lost Negev Highlands desert grape reveals a Late Antiquity wine lineage. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Cohen P   +16 more
europepmc   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang   +10 more
wiley   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

open access: yesAdvanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu   +3 more
wiley   +1 more source

Letter from Paintings of the Year to Fellow Artist (Helen Farr Sloan), April 27, 1948

open access: yes, 1948
1 leaf (single sided)Letter from Paintings of the Year to Fellow Artist (Helen Farr Sloan), April 27 ...
Paintings of the Year
core   +2 more sources

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng   +12 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

open access: yesAdvanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan   +12 more
wiley   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

A comparison of founder-only and all-pedigree-members genotype-expression association by regression analysis-0

open access: yes, 2011
Copyright information:Taken from "A comparison of founder-only and all-pedigree-members genotype-expression association by regression analysis"http://www.biomedcentral.com/1753-6561/1/S1/S8BMC Proceedings 2007;1(Suppl 1):S8-S8.Published online 18 Dec ...
Wentian Li (28857)   +3 more
core   +1 more source

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