Results 161 to 170 of about 23,415,001 (284)

Digital Handwriting Reveals Motor Impairment, Dopaminergic Response, and Progression in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Digital handwriting distinguishes PD patients from healthy controls but is rarely assessed quantitatively. Objectives To evaluate digital handwriting as an objective tool to assess motor impairment, dopaminergic response, and progression in PD.
Lola Díaz‐Feliz, Marcos Faundez‐Zanuy, Andrea Gennari, Alexia Sánchez‐Reyes, Pilar Sanz‐Cartagena, José Arbelo‐González, Miguel Ángel García‐Cabezas, Pedro García‐Ruiz   +7 more
wiley   +1 more source

Integrating Tumour Biology into Surgical Decision-Making for Metastatic Colorectal Cancer: A Real-World Cohort Analysis Adapted for Clinical Colorectal Cancer. [PDF]

Cancers (Basel)
Gonçalves MPC, Trocoli-Couto PHFS, Marchiodi AH, de Carvalho LTB, Yamashita YPH, Lima HA, Resende V.   +6 more
europepmc   +1 more source

HD‐DRUM Rhythmic Training in Huntington's Disease: Feasibility, Motor, and Brain Microstructural Pilot Signals

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Rhythmic cuing may benefit motor functions in Huntington's disease (HD) by compensating for the loss of predictive timing associated with basal ganglia degeneration. To our knowledge no remote rhythmic training application has been developed or evaluated that seeks to improve function in HD.
Pedro Luque Laguna, Vasileios Ioakeimidis, Cheney J.G. Drew, Philip Pallmann, Monica Busse‐Morris, Guy B. Watson, Robin Schubert, Anne E. Rosser, Claudia Metzler‐Baddeley   +8 more
wiley   +1 more source

Transcription termination factor 2 (TTF2) prevents premature rRNA synthesis during mitotic exit. [PDF]

Life Sci Alliance
Pedro C, Tovini L, Peneda C, Krapinec MM, Oliveira RA.   +4 more
europepmc   +1 more source

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota, Jacy B. Parmera, Matheus Deltreggia, Pedro N. Martins, Anna Letícia M. Alves, Ananda C.M. de Falcone, Ana Rosa Santana, Maria Alice P. Falcão, Mayara A. Dias, Larissa I. Moreira, Paulo C. de Fonseca Filho, Eberval G. Figueiredo, Egberto R. Barbosa, Rubens G. Cury, Daniel C. de Andrade   +14 more
wiley   +1 more source

ICTV Virus Taxonomy Profile: <i>Kitaviridae</i> 2026. [PDF]

J Gen Virol
Ramos-González PL, Freitas-Astúa J, Li JM, Tiberini A, Roy A, Yang C.   +5 more
europepmc   +1 more source

Structural Brain and Spinal Cord Signature of Spinocerebellar Ataxia 27B: A Multisite MRI‐Based Study

Movement Disorders, EarlyView.
Abstract Background SCA27B is a recently described ataxia, the precise anatomical basis of which remains unclear. Objective The goal was to characterize the structural brain and spinal cord magnetic resonance imaging (MRI) signature of spinocerebellar ataxia 27B (SCA27B) using multimodal quantitative imaging.
Nadson Bruno Serra Santos, Camila Caroso Lobo, Thiago Junqueira Ribeiro Rezende, Alberto Rolim Muro Martinez, Luiza A. Corazza, Luiz Eduardo Novis, Orlando Graziani Povoas Barsottini, José Luiz Pedroso, Pedro José Tomaselli, Wilson Marques Jr, Antônio Carlos dos Santos, David Pellerin, Bernard Brais, Roberta La Piana, Jemimah Harding, Penny Snell, Paul J. Lockhart, David Szmulewicz, Ian H. Harding, Marcondes Cavalcante França Jr   +19 more
wiley   +1 more source

The complete genome sequences of 22 species of <i>Micromeria</i> (Lamiaceae, Lamiales). [PDF]

Biodivers Genomes
Curto M, Puppo P, Bräuchler C, Jaén-Molina R, Caujapé-Castells J, Pérez de Paz PL, Meimberg H, Pirro S.   +7 more
europepmc   +1 more source

Influence of Fracture Volumetric Intensity on Strength Anisotropy of Foliated Rock Masses: Insights From a Synthetic Rock Mass Modeling Approach

International Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT This paper presents a synthetic rock mass (SRM) methodology to investigate the influence of fracture volumetric intensity (P32$P_{32}$) on the strength anisotropy of foliated rock masses containing non‐persistent fracture sets. The approach integrates UAV‐based discontinuity mapping, discrete fracture network (DFN) modeling, and lattice‐spring
G. G. de Magalhães, P. P. Cacciari, L. Li   +2 more
wiley   +1 more source

Perceived Impacts and Concerns in the Daily Life of People with Chronic Kidney Disease: A Qualitative Study. [PDF]

Port J Public Health
Pedro AR, Raposo B, Cunha AS, Simões C, Brandão D, Martinho H, Bernardo F, Pardal M, Couceiro J, Almeida E.   +9 more
europepmc   +1 more source